Sato Shoichiro, Nakamura Koichiro, Nakahara Toshiki, Yamamoto Teiji
Department of Neurology, Fukushima Medical University.
Rinsho Shinkeigaku. 2005 Aug;45(8):600-2.
A 74-year-old man became unable to walk two days following the initiation of administration of oral distigmine bromide, 10 mg per day, for his constipation. Neurological examination revealed bradykinesia, rigidity and fine postural tremor without laterality. T2 weighted MRI showed mild front-temporal atrophy and multiple hyperintensities in both deep white matters. His symptoms fully improved one week after discontinuance of distigmine bromide. This is the first case report of distigmine bromide induced Parkinsonism.
一名74岁男性因便秘开始口服溴化地斯的明，每日10毫克，两天后出现行走困难。神经系统检查发现有运动迟缓、僵硬和无偏侧性的精细姿势性震颤。T2加权磁共振成像显示轻度额颞叶萎缩以及双侧深部白质多发高信号。停用溴化地斯的明一周后，他的症状完全改善。这是溴化地斯的明诱发帕金森综合征的首例病例报告。
Zotero 插件