红毛丹种子中的单萜内酯

Monoterpene lactones from the seeds of Nephelium lappaceum.

作者信息

Ragasa Consolacion Y, de Luna Roderick D, Cruz Wilfredo C, Rideout John A

机构信息

Chemistry Department, De La Salle University, 2401 Taft Avenue, Manila, 1004, Philippines.

出版信息

J Nat Prod. 2005 Sep;68(9):1394-6. doi: 10.1021/np0580053.

DOI:10.1021/np0580053

PMID:16180821

Abstract

Dichloromethane extracts of the seeds of Nephelium lappaceum afforded two new diastereomeric monoterpene lactones, 1 and 2, and the known butenolide siphonodin (3), as well as kaempferol 3-O-beta-D-glucopyranoside-7-O-alpha-L-rhamnopyranoside. Compounds 1 and 2 represent a new monoterpene skeleton, and their structures were elucidated by extensive 1D and 2D NMR spectral data interpretation. Antimicrobial testing was carried out on 1 and 2 against a panel of bacteria and fungi.

摘要

红毛丹种子的二氯甲烷提取物得到了两种新的非对映体单萜内酯1和2、已知的丁烯内酯西佛诺定（3）以及山柰酚3 - O - β - D - 吡喃葡萄糖苷 - 7 - O - α - L - 吡喃鼠李糖苷。化合物1和2代表一种新的单萜骨架，通过广泛的一维和二维核磁共振光谱数据解析阐明了它们的结构。对化合物1和2针对一组细菌和真菌进行了抗菌测试。