来自栀子的环烯醚萜类化合物。
Iridoids from Gardenia jasminoides.
作者信息
Ragasa Consolacion Y, Pimenta Leslie Elline N, Rideout John A
机构信息
Chemistry Department, De La Salle University, Manila, Philippines.
出版信息
Nat Prod Res. 2007 Oct;21(12):1078-84. doi: 10.1080/14786410701589998.
The dichloromethane extract of the air-dried flowers of Gardenia jasminoides Ellis. afforded a new iridoid natural product (1), and a diastereomeric mixture of two new iridoids (2a and 2b) in a 2 : 1 ratio. Their structures were elucidated by extensive 1D and 2D NMR spectroscopy. Antimicrobial tests on 1 indicated that it was moderately active against Candida albicans; slightly active against E. coli, Pseudomonas aeruginosa, Staphylococcus. aureus, and Trichophyton mentagrophytes; and inactive against Bacillus subtilis and Aspergillus niger.
栀子（Gardenia jasminoides Ellis.）风干花的二氯甲烷提取物得到一种新的环烯醚萜天然产物（1），以及两种新环烯醚萜（2a和2b）的非对映异构体混合物，比例为2:1。通过广泛的一维和二维核磁共振光谱对其结构进行了阐明。对1的抗菌测试表明，它对白色念珠菌有中等活性；对大肠杆菌、铜绿假单胞菌、金黄色葡萄球菌和须癣毛癣菌有轻微活性；对枯草芽孢杆菌和黑曲霉无活性。
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