Mystakidou Kyriaki, Parpa Efi, Katsouda Emmanuela, Galanos Antonis, Vlahos Lambros
Pain Relief and Palliative Care Unit, Department of Radiology, Areteion Hospital, School of Medicine, University of Athens, 27 Korinthias Str., 115 26 Athens, Greece.
Psychooncology. 2006 Apr;15(4):355-60. doi: 10.1002/pon.972.
The current study assessed the attitudes of the desire for hastened death in terminally ill cancer patients and whether these are determined by their physical and psychological symptoms. The final sample consisted of 106 terminally ill cancer patients attending a Palliative Care Unit, in University of Athens, Greece, between June and October 2004. Significant associations were found between the desire for hastened death (D.H.D.) and 'pain' (r=0.469, p<0.005), 'fatigue' (r=0.591, p<0.0005), 'loss of appetite' (r=0.622, p<0.0005) and 'feeling sad' (r=0.635, p<0.0005). Statistically significant associations were also found between Schedule of Attitudes towards Hastened Death (SAHD) scores, age (r=0.300, p=0.002) and ECOG (p<0.0005). Twenty-six percent of the patients reported high D.H.D. while 41% reported moderate desire. In the prediction of SHAD the contribution of 'pain' (p=0.011), 'lack of appetite' (p=0.012) and 'sadness' (p=0.011) is high (42% of variance). Further findings suggest that D.H.D. is significantly related to 'feeling sad', 'lack of appetite', 'pain' and 'fatigue' after controlling for age, gender and performance status according to ECOG in terminally ill cancer patients.
本研究评估了晚期癌症患者对加速死亡的渴望态度,以及这些态度是否由其身体和心理症状所决定。最终样本包括2004年6月至10月间在希腊雅典大学姑息治疗科就诊的106例晚期癌症患者。研究发现,对加速死亡的渴望(D.H.D.)与“疼痛”(r = 0.469,p < 0.005)、“疲劳”(r = 0.591,p < 0.0005)、“食欲不振”(r = 0.622,p < 0.0005)和“悲伤情绪”(r = 0.635,p < 0.0005)之间存在显著关联。对加速死亡态度量表(SAHD)得分与年龄(r = 0.300,p = 0.002)和东部肿瘤协作组(ECOG)评分(p < 0.0005)之间也存在统计学显著关联。26%的患者报告有较高的加速死亡渴望,41%的患者报告有中度渴望。在预测SAHD时,“疼痛”(p = 0.011)、“食欲不振”(p = 0.012)和“悲伤情绪”(p = 0.011)的贡献率较高(占方差的42%)。进一步研究结果表明,在控制晚期癌症患者的年龄、性别和根据ECOG评估的体能状态后,加速死亡渴望与“悲伤情绪”、“食欲不振”、“疼痛”和“疲劳”显著相关。