Bergdahl Ellinor, Gustavsson Janna M C, Kallin Kristina, von Heideken Wågert Petra, Lundman Berit, Bucht Gästa, Gustafson Yngve
Department of Community Medicine and Rehabilitation, Geriatric Medicine, Umeå University, Umeå, Sweden.
Int Psychogeriatr. 2005 Dec;17(4):557-75. doi: 10.1017/S1041610205002267. Epub 2005 Sep 27.
To investigate the prevalence of depression among the oldest old and to analyze factors associated with depression.
A cross-sectional, population-based study was undertaken in Umeå, Sweden. Out of 319 eligible participants aged 85, 90 and 95 years and older, it was possible to evaluate 242 people (75.9%) for depression. Data were collected from structured interviews and assessments in the participants' homes, and from medical charts, relatives and caregivers. Depression was screened for using the Geriatric Depression Scale-15 and further assessed with the Montgomery-Asberg Depression Rating Scale. Cognition was assessed using the Mini-mental State Examination, activities of daily living (ADL) using the Barthel ADL Index, nutrition using the Mini Nutritional Assessment and well-being using the Philadelphia Geriatric Center Morale Scale.
The 85-year-olds had a significantly lower prevalence of depression than the 90- and 95-year-olds (16.8% vs. 34.1% and 32.3%). No sex differences were found. One-third of those with depression had no treatment and among those with ongoing treatment 59% were still depressed. Persons diagnosed with depression had a poorer well-being and a higher 1-year mortality. Logistic regression analyses showed that depression was independently associated with living in institutions and number of medications.
Depression among the oldest old is common, underdiagnosed and inadequately treated, and causes poor well-being and increased mortality. More knowledge about depression is essential to improve the assessment and treatment of depression among the oldest old.
调查高龄老年人中抑郁症的患病率,并分析与抑郁症相关的因素。
在瑞典于默奥开展了一项基于人群的横断面研究。在319名年龄为85岁、90岁、95岁及以上的符合条件的参与者中,有242人(75.9%)能够接受抑郁症评估。数据通过在参与者家中进行的结构化访谈和评估、医疗记录、亲属及照料者收集。使用老年抑郁量表-15进行抑郁症筛查,并进一步用蒙哥马利-艾斯伯格抑郁评定量表进行评估。使用简易精神状态检查表评估认知功能,使用巴氏日常生活活动指数评估日常生活活动能力(ADL),使用微型营养评定量表评估营养状况,使用费城老年中心士气量表评估幸福感。
85岁老年人的抑郁症患病率显著低于90岁和95岁老年人(16.8%对34.1%和32.3%)。未发现性别差异。三分之一的抑郁症患者未接受治疗,在接受持续治疗的患者中,59%仍处于抑郁状态。被诊断为抑郁症的人幸福感较差,1年死亡率较高。逻辑回归分析表明,抑郁症与住在养老院和用药数量独立相关。
高龄老年人中的抑郁症很常见,诊断不足且治疗不充分,会导致幸福感差和死亡率增加。更多关于抑郁症的知识对于改善高龄老年人抑郁症的评估和治疗至关重要。