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年龄相关性听力损失与抑郁症之间的关联:一项系统评价和荟萃分析。

Association between age-related hearing loss and depression: A systematic review and meta-analysis.

作者信息

Li Fuyao, Jin Meiling, Ma Tianyi, Cui Chunlian

机构信息

Department of Otolaryngology Head and Neck Surgery, Yanbian University Affiliated Hospital, Yanji City, Yanbian Korean Autonomous Prefecture, Jilin Province, China.

出版信息

PLoS One. 2025 Jan 3;20(1):e0298495. doi: 10.1371/journal.pone.0298495. eCollection 2025.

Abstract

INTRODUCTION

This meta-analysis examined the relationship between age-related hearing loss (ARHL) and depression in older adults, and further explored whether this relationship is moderated by age and gender.

METHODS

We searched in 4 English databases: PubMed, Embase, Web of Science, and Cochrane Library. Ultimately, we identified 9 studies, involving 3 cohort studies and 6 cross-sectional studies. We used Hedges' g as the effect size, and all pooled analyses were performed using random-effects models.

RESULTS

ARHL patients had higher depressive symptom scores than non-ARHL older adults (g = 0.52). When divided into subgroups based on study type, a large effect size was demonstrated in the cross-sectional study group (g = 0.68) and was not statistically different in the cohort study group (g = 0.06). Meta-regression results showed that the effect size of depression in older adults with ARHL was significantly associated with the percentage of females (t = 5.97, p = 0.000) and not significantly associated with age (t = 0.94, p = 0.364).

CONCLUSIONS

Patients with ARHL are more likely to be depressed than older adults with normal hearing, and this relationship is influenced by the gender of the patients.

摘要

引言

本荟萃分析研究了老年人年龄相关性听力损失(ARHL)与抑郁症之间的关系,并进一步探讨了这种关系是否受年龄和性别的调节。

方法

我们在4个英文数据库中进行了检索:PubMed、Embase、科学网和考克兰图书馆。最终,我们确定了9项研究,其中包括3项队列研究和6项横断面研究。我们使用Hedges' g作为效应量,所有汇总分析均采用随机效应模型进行。

结果

ARHL患者的抑郁症状评分高于听力正常的老年人(g = 0.52)。按研究类型分为亚组时,横断面研究组显示出较大的效应量(g = 0.68),队列研究组则无统计学差异(g = 0.06)。荟萃回归结果表明,ARHL老年人的抑郁效应量与女性比例显著相关(t = 5.97,p = 0.000),与年龄无显著相关性(t = 0.94,p = 0.364)。

结论

与听力正常的老年人相比,ARHL患者更易患抑郁症,且这种关系受患者性别的影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0877/11698527/7a59c10f2fd4/pone.0298495.g001.jpg

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