Li Fuyao, Jin Meiling, Ma Tianyi, Cui Chunlian
Department of Otolaryngology Head and Neck Surgery, Yanbian University Affiliated Hospital, Yanji City, Yanbian Korean Autonomous Prefecture, Jilin Province, China.
PLoS One. 2025 Jan 3;20(1):e0298495. doi: 10.1371/journal.pone.0298495. eCollection 2025.
This meta-analysis examined the relationship between age-related hearing loss (ARHL) and depression in older adults, and further explored whether this relationship is moderated by age and gender.
We searched in 4 English databases: PubMed, Embase, Web of Science, and Cochrane Library. Ultimately, we identified 9 studies, involving 3 cohort studies and 6 cross-sectional studies. We used Hedges' g as the effect size, and all pooled analyses were performed using random-effects models.
ARHL patients had higher depressive symptom scores than non-ARHL older adults (g = 0.52). When divided into subgroups based on study type, a large effect size was demonstrated in the cross-sectional study group (g = 0.68) and was not statistically different in the cohort study group (g = 0.06). Meta-regression results showed that the effect size of depression in older adults with ARHL was significantly associated with the percentage of females (t = 5.97, p = 0.000) and not significantly associated with age (t = 0.94, p = 0.364).
Patients with ARHL are more likely to be depressed than older adults with normal hearing, and this relationship is influenced by the gender of the patients.
本荟萃分析研究了老年人年龄相关性听力损失（ARHL）与抑郁症之间的关系，并进一步探讨了这种关系是否受年龄和性别的调节。
我们在4个英文数据库中进行了检索：PubMed、Embase、科学网和考克兰图书馆。最终，我们确定了9项研究，其中包括3项队列研究和6项横断面研究。我们使用Hedges' g作为效应量，所有汇总分析均采用随机效应模型进行。
ARHL患者的抑郁症状评分高于听力正常的老年人（g = 0.52）。按研究类型分为亚组时，横断面研究组显示出较大的效应量（g = 0.68），队列研究组则无统计学差异（g = 0.06）。荟萃回归结果表明，ARHL老年人的抑郁效应量与女性比例显著相关（t = 5.97，p = 0.000），与年龄无显著相关性（t = 0.94，p = 0.364）。
与听力正常的老年人相比，ARHL患者更易患抑郁症，且这种关系受患者性别的影响。
