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极高龄人群中中风的患病率以及中风与抑郁之间的关系。

The prevalence of stroke and the association between stroke and depression among a very old population.

机构信息

Department of Community Medicine and Rehabilitation, Geriatric Medicine, Umeå University, SE-90185 Umeå, Sweden.

出版信息

Arch Gerontol Geriatr. 2012 Nov-Dec;55(3):555-9. doi: 10.1016/j.archger.2012.04.012. Epub 2012 May 28.

DOI:10.1016/j.archger.2012.04.012
PMID:22647381
Abstract

There are few studies comparing those who have had and have not had a stroke among those aged 80 years and over, the very old. The aim of this paper was to investigate the prevalence of stroke and the association between stroke and depression in a very old population. This paper is based on cross-sectional data from a population-based study performed between 2005 and 2007. Half of those aged 85 years, all 90-, and 95-year-olds and older in eight urban and rural municipalities in northern Sweden and Finland were invited to participate. A sample of 601 individuals who participated fully in the study was selected. Data were collected through assessments, structured interviews and investigation of medical charts. A specialist in geriatric medicine determined disease status for depression based on medical records and results from the Geriatric Depression Scale (GDS)-15, the Montgomery Åsberg Depression Rating Scale (MADRS) and the Organic Brain Syndrome (OBS) scale, and for stroke based on medical records and reported disease. The prevalence of stroke was 21.5%. The prevalence of depression was 50.4% among those with stroke compared to 34.3% among those without stroke (OR 1.944, p<0.001). In a logistic regression model adjusted for several demographic variables, diseases and functional level, stroke was independently associated with depression (OR 1.644, p=0.038). A large proportion of those with depression, both with and without stroke, were not receiving antidepressant medication. In conclusion, the stroke prevalence was high and stroke showed a strong association with depression among very old people.

摘要

在 80 岁及以上的老年人中,即非常老年人中,很少有研究比较那些曾经患过中风和没有患过中风的人。本文的目的是调查非常老年人中风的患病率以及中风与抑郁之间的关系。本文基于 2005 年至 2007 年期间进行的一项基于人群的研究的横断面数据。瑞典和芬兰北部 8 个城乡市的所有 85 岁及以上的人群的一半,所有 90 岁及以上的人群和 95 岁及以上的人群都被邀请参加。选择了 601 名充分参与研究的个体作为样本。通过评估、结构化访谈和病历调查收集数据。一名老年医学专家根据病历和老年抑郁量表(GDS-15)、蒙哥马利抑郁评定量表(MADRS)和器质性脑综合征(OBS)量表的结果,以及根据病历和报告的疾病确定抑郁状态的疾病状况,确定中风状态。中风的患病率为 21.5%。患有中风的人群中,抑郁的患病率为 50.4%,而没有中风的人群中,抑郁的患病率为 34.3%(OR 1.944,p<0.001)。在调整了几个人口统计学变量、疾病和功能水平的逻辑回归模型中,中风与抑郁独立相关(OR 1.644,p=0.038)。患有抑郁的人群中,无论是否患有中风,很大一部分人都没有服用抗抑郁药物。总之,中风的患病率很高,而且在非常老年人中,中风与抑郁之间存在很强的关联。

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