Ariyama J, Shirakabe H, Shimaguchi S, Schmidt L
Rofo. 1979 Dec;131(6):610-5. doi: 10.1055/s-0029-1231502.
Sixty-five patients with obstructive jaundice out of a total of 71 patients, were treated successfully by PTCD. The markedly elevated total bilirubin and alkaline phosphatase in the serum were reduced significantly and the general condition of the patient improved rapidly. On the other hand, severe obstructive jaundice which had persisted for several weeks was not amenable to treatment in this way. Occlusion of the extrahepatic bile ducts by tumour was treated by internal PTCD; this provided satisfactory flow of bile into the duodenum for at least six months. PTCD is simpler for the patient than surgery and is therefore the method of choice in obstructive jaundice. Finally, PTCD can be used for the introduction of antibiotics for the treatment of suppurative cholangitis or liver abscesses. This rapidly leads to reduction in fever and absorption of the abscesses.
71例患者中，65例梗阻性黄疸患者通过经皮肝穿刺胆管引流术（PTCD）成功治愈。血清中显著升高的总胆红素和碱性磷酸酶明显降低，患者的一般状况迅速改善。另一方面，持续数周的严重梗阻性黄疸无法通过这种方式治疗。肝外胆管被肿瘤阻塞则采用经皮肝穿刺胆管内引流术治疗；这使胆汁至少六个月内都能顺利流入十二指肠。对患者而言，PTCD比手术更简便，因此是梗阻性黄疸的首选治疗方法。最后，PTCD可用于引入抗生素来治疗化脓性胆管炎或肝脓肿。这能迅速降低体温并使脓肿吸收。
