Gong Gaolang, Jiang Tianzi, Zhu Chaozhe, Zang Yufeng, He Yong, Xie Sheng, Xiao Jiangxi
National Laboratory of Pattern Recognition, Institute of Automation, Chinese Academy of Sciences, Beijing.
Neuroreport. 2005 Oct 17;16(15):1701-5. doi: 10.1097/01.wnr.0000183327.98370.6a.
In order to explore the microstructure of bilateral cingulum bundles associated with side and handedness, fractional anisotropy was extracted from diffusion tensor imaging. Distinguished from the conventional region of interest-based method, a fiber-based analysis method called scale-invariant parameterization method was employed to ascertain the anisotropy along the cingulum bundle in 31 normal right-handers and 14 normal left-handers. The statistical results showed a remarkable left-greater-than-right asymmetry pattern of anisotropy in most segments of cingulum bundles except the most posterior segment, for both right-handers and left-handers. Interestingly, higher anisotropy of the right-hander than the left-hander was found in the bilateral cingulum bundles. No significant handedness-by-side interaction was obtained in the present study, however.
为了探究与利手和脑半球相关的双侧扣带束的微观结构，从扩散张量成像中提取了分数各向异性。与传统的基于感兴趣区域的方法不同，本研究采用了一种基于纤维的分析方法——尺度不变参数化方法，来确定31名正常右利手者和14名正常左利手者扣带束的各向异性。统计结果显示，除最靠后的节段外，右利手者和左利手者扣带束的大多数节段都呈现出显著的左大于右的各向异性不对称模式。有趣的是，在双侧扣带束中发现右利手者的各向异性高于左利手者。然而，在本研究中未获得显著的利手与脑半球交互作用。
