Praeg Elke, Herwig Uwe, Lutz Kai, Jancke Lutz
Department of Neuropsychology, Institute of Psychology, University of Zurich, Switzerland.
Neuroreport. 2005 Oct 17;16(15):1715-8. doi: 10.1097/01.wnr.0000183333.36488.1c.
To study the role of the right dorsal premotor cortex in visuomotor association learning (association of four visual stimuli to four buttons), transcranial magnetic stimulation was applied to this area to interfere with the ongoing learning processes. Two transcranial magnetic stimulation pulses to the right dorsal premotor cortex at 150 and 200 ms after onset of the imperative stimulus resulted in the abolishing of reaction time decreases during learning. Transcranial magnetic stimulation applied to a control region revealed no influence on reaction time decreases. During both conditions, however, there were similar increases of accuracy scores. We conclude that the right dorsal premotor cortex is not directly involved in associating visual with motor cues. We suggest that this area is intimately involved in selection and preparation of forthcoming movements.
为研究右侧背侧运动前区皮质在视觉运动联合学习（将四种视觉刺激与四个按钮建立联系）中的作用，对该区域施加经颅磁刺激以干扰正在进行的学习过程。在指令性刺激开始后150毫秒和200毫秒时，对右侧背侧运动前区皮质施加两个经颅磁刺激脉冲，导致学习过程中反应时间的缩短被消除。对一个对照区域施加经颅磁刺激则显示对反应时间的缩短没有影响。然而，在两种情况下，准确率得分都有类似的提高。我们得出结论，右侧背侧运动前区皮质并不直接参与视觉与运动线索的关联。我们认为该区域密切参与即将进行的运动的选择和准备。
