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前列腺半切除术:与标准经尿道切除术的短期随机对照比较

Hemiresection of the prostate: short-term randomized comparison with standard transurethral resection.

作者信息

Agrawal Madhu S, Aron Monish, Goel Rajiv

机构信息

Department of Urology, SN Medical College, Agra, India.

出版信息

J Endourol. 2005 Sep;19(7):868-72. doi: 10.1089/end.2005.19.868.

DOI:10.1089/end.2005.19.868
PMID:16190847
Abstract

BACKGROUND AND PURPOSE

During transurethral resection of the prostate (TURP) for a very large and vascular gland in a medically compromised patient, there may arise the need for quick termination of the procedure because of medical problems that develop as a result of fluid absorption or bleeding if the surgery is prolonged. In such a situation, an alternative solution proposed by us is termination of the procedure after complete resection of one lateral lobe (and the median lobe, if present) of the prostate (hemiresection).

PATIENTS AND METHODS

From January 1998 to December 2001, 161 consecutive symptomatic men with prostates >50 cc and an indication for prostatectomy were randomized to receive either a standard TURP (group 1; 80 patients) or prostatic hemiresection; i.e., complete resection of one lateral lobe and the median lobe, if present (group 2; 81 patients). The two groups were comparable in terms of age and prostate size. Preoperative and postoperative parameters were compared in the two groups using Student's t-test.

RESULTS

Resected tissue weight was significantly greater in group 1, while the resection time and operative blood loss were significantly lower in group 2. The two groups had comparable improvement in symptom score and flow rate.

CONCLUSIONS

Hemiresection of the prostate produces short-term functional results comparable to those of standard TURP in patients with prostates >50 cc, with shorter operative duration and significantly less bleeding. It is an acceptable surgical option in medically compromised patients with significant cardiac, pulmonary, or renal comorbidity.

摘要

背景与目的

在对一名存在医疗风险的患者进行经尿道前列腺切除术(TURP)时,如果前列腺体积非常大且血管丰富,若手术时间延长,因液体吸收或出血引发的医疗问题可能导致需要迅速终止手术。在这种情况下,我们提出的一种替代解决方案是在完全切除前列腺的一个侧叶(以及中叶,如果存在)后终止手术(半切除)。

患者与方法

从1998年1月至2001年12月,161例有症状且前列腺体积>50 cc并具有前列腺切除术指征的连续男性患者被随机分为接受标准TURP组(第1组;80例患者)或前列腺半切除术组,即完全切除一个侧叶以及中叶(如果存在)(第2组;81例患者)。两组在年龄和前列腺大小方面具有可比性。使用学生t检验比较两组的术前和术后参数。

结果

第1组切除组织重量显著更大,而第2组的切除时间和术中失血量显著更低。两组在症状评分和流速改善方面具有可比性。

结论

对于前列腺体积>50 cc的患者,前列腺半切除术产生的短期功能结果与标准TURP相当,手术持续时间更短且出血显著更少。对于存在严重心脏、肺部或肾脏合并症的医疗风险患者,这是一种可接受的手术选择。

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