Turgut Ömer, Erbagcı Ahmet, Bayrak Omer, Seckiner Ilker, Erturhan Sakıp, Sen Haluk, Ozturk Mehmet
Urology, Besni State Hospital, Adıyaman, TUR.
Urology, Gaziantep University Medical Faculty, Gaziantep, TUR.
Cureus. 2023 Jan 31;15(1):e34451. doi: 10.7759/cureus.34451. eCollection 2023 Jan.
The present study assesses the effect of the proportion of tissue resected during transurethral resections of the prostate (TUR-P) on lower urinary tract symptoms (LUTS) and other parameters in patients with a benign prostatic obstruction (BPO).
Forty-three patients who underwent TUR-P between 2018 and 2021 were assessed prospectively. The patients were divided into two groups according to the percentage of tissue removed (group 1 <30%, group 2 >30% resection). Age, prostate volume, amount of resected tissue, operative time, length of hospital stay, duration of catheterization, International Prostate Symptom Score (IPSS), quality of life score (QoL), maximum urinary flow rate (Qmax), and serum prostate-specific antigen (PSA) (ng/dl) at preoperative and postoperative three months were recorded.
The percentage of tissue removed was 22.2% vs. 48.4% (p = 0.001), IPSS reduction was 77.7% vs. 83.3% (p = 0.048), QoL improvement was 77.2% vs. 84.8% (p = 0.133), Qmax increase was 171.3% vs. 193.5% (p = 0.032), and serum PSA decrease was 56.4% vs. 69.2% (p = 0.049) in groups 1 and 2, respectively. In addition, the operative time was 38.5 vs. 53.6 min (p = 0.001), the length of hospital stay was 2.0 vs. 2.4 days (p = 0.001), and the duration of catheterization average was 4.1 vs. 4.9 days (p = 0.002).
Resections of at least 30% of prostatic tissue can provide a significant improvement in the symptoms and parameters related to benign prostatic obstruction, while resections of less than 30% of prostatic tissue can effectively reduce urinary symptoms and improve the quality of life in older adult patients with comorbidities who require shorter operating times.
本研究评估经尿道前列腺切除术（TUR-P）中切除组织比例对良性前列腺梗阻（BPO）患者下尿路症状（LUTS）及其他参数的影响。
对2018年至2021年间接受TUR-P的43例患者进行前瞻性评估。根据切除组织的百分比将患者分为两组（第1组<30%，第2组>30%切除）。记录患者术前及术后三个月的年龄、前列腺体积、切除组织量、手术时间、住院时间、导尿时间、国际前列腺症状评分（IPSS）、生活质量评分（QoL）、最大尿流率（Qmax）以及血清前列腺特异性抗原（PSA）（ng/dl）。
第1组和第2组的切除组织百分比分别为22.2%和48.4%（p = 0.001），IPSS降低分别为77.7%和83.3%（p = 0.048），QoL改善分别为77.2%和84.8%（p = 0.133），Qmax增加分别为171.3%和193.5%（p = 0.032），血清PSA降低分别为56.4%和69.2%（p = 0.049）。此外，手术时间分别为38.5分钟和53.6分钟（p = 0.001），住院时间分别为2.0天和2.4天（p = 0.001），平均导尿时间分别为4.1天和4.9天（p = 0.002）。
切除至少30%的前列腺组织可显著改善与良性前列腺梗阻相关的症状和参数，而切除少于30%的前列腺组织可有效减轻老年合并症患者的尿路症状并改善生活质量，且这些患者需要较短的手术时间。
