Guan Peng, Tajimi Morihiro, Uehara Ritei, Watanabe Makoto, Oki Izumi, Ojima Toshiyuki, Nakamura Yosikazu
Department of Public Health, Jichi Medical School, Minamikawachi,Tochigi, Japan.
Pediatr Int. 2005 Oct;47(5):560-6. doi: 10.1111/j.1442-200x.2005.02121.x.
The presence of dioxins in breast milk has gained much attention recently. However, in Japan the relationship between the consumption of different foods and the human breast milk dioxin concentrations is still unclear.
Breast milk was taken from 240 mothers residing in Tokyo, Japan to measure and analyze the concentrations of polychlorinated dibenzo-p-dioxins, polychlorinated dibenzofurans, and coplanar poly-chlorinated biphenyls contained in the fat. Individual milk samples were obtained from the mothers 30 days after delivery in 1999 and 2000. The data of the mothers' diets before pregnancy were collected by means of food frequency and amount estimation. Spearman correlation analysis and stepwise multiple linear regression were used to analyze the data.
The concentrations of dioxins in breast milk were influenced mainly by the mother's age and history of breast-feeding. All the Spearman correlation coefficients were less than 0.20. Pork, roast ham, sausage, salt codfish and tempura had negative correlations with breast milk dioxins.
History of breast-feeding and the mother's age should be considered and emphasized in this kind of analysis. The cause effect relationship between dietary intake and breast milk dioxin levels were still uncertain.
母乳中存在二噁英最近备受关注。然而，在日本，不同食物的摄入量与母乳中二噁英浓度之间的关系仍不明确。
采集了居住在日本东京的240名母亲的母乳，以测量和分析脂肪中所含的多氯二苯并对二噁英、多氯二苯并呋喃和共面多氯联苯的浓度。1999年和2000年，在母亲分娩30天后采集个体母乳样本。通过食物频率和摄入量估计收集母亲孕前饮食的数据。采用Spearman相关性分析和逐步多元线性回归对数据进行分析。
母乳中二噁英的浓度主要受母亲年龄和母乳喂养史的影响。所有Spearman相关系数均小于0.20。猪肉、烤火腿、香肠、咸鳕鱼和天妇罗与母乳中的二噁英呈负相关。
在这类分析中应考虑并强调母乳喂养史和母亲年龄。饮食摄入量与母乳中二噁英水平之间的因果关系仍不确定。
