Fujishiro Takaaki, Nishikawa Tetsuo, Niikura Takahiro, Takikawa Satoshi, Nishiyama Takayuki, Mizuno Kiyonori, Yoshiya Shinichi, Kurosaka Masahiro
Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine, Japan.
Acta Orthop. 2005 Aug;76(4):550-4. doi: 10.1080/17453670510041556.
Substantial bone loss and bone defects increase the amount of allografting required in hip revision surgery. Thus, the use of a synthetic material to limit the amount of allograft tissue required for impaction grafting is desirable. We evaluated the potential of hydroxyapatite (HA) mixtures to provide initial mechanical stability to a polished tapered femoral stem.
We determined the initial stability of a polished tapered femoral stem after reconstructing a cavitary femoral bone defect by impaction bone grafting with cement in Sawbones composite femurs. Three types of graft material were tested for their ability to improve initial rotational stability. The graft materials investigated were pure allograft, a mixture of 50% allograft and 50% hydroxyapatite (HA), and pure HA.
We found a statistically significant difference between the three groups as regards torsional micromotion and failure load.
Our findings suggest that reconstruction of femoral bone defects with pure HA or a mixture of allograft and HA provides adequate initial stability for femoral revision arthroplasty using impaction grafting.
大量的骨质流失和骨缺损增加了髋关节翻修手术中所需的同种异体骨移植量。因此，使用合成材料来限制打压植骨所需的同种异体骨组织量是很有必要的。我们评估了羟基磷灰石（HA）混合物为抛光锥形股骨柄提供初始机械稳定性的潜力。
在用Sawbones复合股骨通过骨水泥打压植骨重建股骨腔骨缺损后，我们测定了抛光锥形股骨柄的初始稳定性。测试了三种移植材料改善初始旋转稳定性的能力。所研究的移植材料为纯同种异体骨、50%同种异体骨和50%羟基磷灰石（HA）的混合物以及纯HA。
我们发现三组在扭转微动和破坏载荷方面存在统计学上的显著差异。
我们的研究结果表明，使用纯HA或同种异体骨与HA的混合物重建股骨骨缺损可为采用打压植骨的股骨翻修关节成形术提供足够的初始稳定性。
