Rupnik Helena, Podrumac Bozana, Zgavec Borut, Lunder Tomaz
Dept of Dermatovenereology, University Medical Centre Ljubljana, Zaloska 2, 1525 Ljubljana, Slovenia.
Acta Dermatovenerol Alp Pannonica Adriat. 2005 Sep;14(3):111-4.
Follicular mucinosis is characterized by mucin deposits within the hair follicles and sebaceous glands. It can occur as a primary idiopathic benign disorder; it can be found as an incidental phenomenom in rare cases of different dermatoses; or it can arise as a secondary symptom of a malignant disorder, most commonly mycosis fungoides. Youth and localization in a single area used to be regarded as indicative of the benign nature of follicular mucinosis. However, recent reports demonstrate that no clear-cut criteria allow for the differentiation of idiopathic from lymphoma-associated follicular mucinosis. We report the case of a 16-year old girl who presented with a 2-year history of a single, slightly pruritic, erythematous patch on the left side of the neck. Different local treatments (local corticosteroids, antibiotics, antifungal ointments and moisturizers) were ineffective. Overall, she was healthy. Histopathological examination of the lesion showed the typical histological picture of follicular mucinosis.
毛囊黏蛋白沉积症的特征是毛囊和皮脂腺内有黏蛋白沉积。它可作为一种原发性特发性良性疾病出现；在罕见的不同皮肤病病例中可作为偶然现象被发现；或者可作为恶性疾病的继发症状出现，最常见的是蕈样肉芽肿。过去，发病于年轻人且局限于单一部位被认为是毛囊黏蛋白沉积症良性性质的指征。然而，最近的报告表明，没有明确的标准能够区分特发性毛囊黏蛋白沉积症和淋巴瘤相关的毛囊黏蛋白沉积症。我们报告了一名16岁女孩的病例，她左侧颈部有一个单一的、轻度瘙痒的红斑，病史为2年。不同的局部治疗方法（局部使用皮质类固醇、抗生素、抗真菌药膏和保湿剂）均无效。总体而言，她身体健康。病变的组织病理学检查显示出毛囊黏蛋白沉积症的典型组织学表现。
