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毛囊黏蛋白沉积症——病例报告。

Follicular mucinosis - case report.

作者信息

Passos Paola C Vieira da Rosa, Zuchi Manuela Ferrasso, Fabre Andréa Buosi, Martins Luis Eduardo A Machado

机构信息

Faculdade Evangélica do Paraná, Curitiba, PR, Brazil.

出版信息

An Bras Dermatol. 2014 Mar-Apr;89(2):337-9. doi: 10.1590/abd1806-4841.20142968.

Abstract

Follicular mucinosis, also known as alopecia mucinosa, is a cutaneous mucinosis histologically characterized by accumulation of dermal type mucin in the pilosebaceous follicle and sebaceous glands. It presents in two forms, a primary or idiopathic form and a secondary form associated with various benign or malignant processes. Among the malignant processes, the main association is with mycosis fungoides. The frequent overlap of clinical, histopathological, immunohistochemical and molecular biology characteristics makes the correct classification of these conditions difficult, therefore a long follow-up of all cases is recommended. We report the case of an adolescent with disseminated lesions and discuss the difficulty of early identification of secondary follicular mucinosis associated with cutaneous lymphoma.

摘要

毛囊黏蛋白沉积症,又称黏液性秃发,是一种皮肤黏蛋白沉积症,组织学特征为真皮型黏蛋白在毛囊和皮脂腺中积聚。它有两种表现形式,一种是原发性或特发性形式,另一种是与各种良性或恶性病变相关的继发性形式。在恶性病变中,主要与蕈样肉芽肿相关。临床、组织病理学、免疫组织化学和分子生物学特征的频繁重叠使得对这些病症进行正确分类变得困难,因此建议对所有病例进行长期随访。我们报告了一例患有播散性病变的青少年病例,并讨论了早期识别与皮肤淋巴瘤相关的继发性毛囊黏蛋白沉积症的困难。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a61/4008071/134f4374465b/abd-89-02-0337-g01.jpg

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