Liu Xing, Liang Yuan-bo, Ling Yun-lan, Zheng Xiao-ping
Zhongshan Ophthalmic Center, Zhongshan University, Guangzhou 510060, China.
Zhonghua Yan Ke Za Zhi. 2004 Oct;40(10):683-8.
To study the optic nerve head (ONH) parameters and topograph features of normal subjects, and analyze the effect of gender, laterality, age and disc size on the topograph of ONH.
Heidelberg Retina Tomograph (HRT) was used to obtain the optic nerve head parameters and topograph images in 216 eyes of 116 normal volunteers. The impact of gender, laterality, age and disc size on the topograph was analyzed. The optic disc was divided into three groups by their size, small (less than 1.5 mm2), middle and large disc (equal or larger than 2.5 mm2), to evaluate the differences of parameters.
The parameters of ONH in normal eyes were as following: disc area (DA) (2.208 +/- 0.411) mm, cup area (CA) (0.466 +/- 0.355) mm2, cup/disk area ratio (C/DAR) (0.217 +/- 0.137), rim area (RA) (1.563 +/- 0.339) mm2, height variation contour (HVC) (0.404 +/- 0.096) mm, cup volume (CV) 0.127 mm3, rim volume (RV) (0.446 +/- 0.173) mm3, mean cup depth (MCD) (0.196 +/- 0.096) mm, maximum cup depth (MxCD) (0.559 +/- 0.228) mm, cup shape measure (CSM) (-0.213 +/- 0.076), mean retinal nerve fiber layer thickness (mRNFLT) (0.272 +/- 0.076) mm, and retinal nerve fiber layer cross section area (RNFLA) (1.364 +/- 0.375) mm2. There were significant differences between right and left eyes in C/DAR, RA and RV, but no difference between different genders in all parameters. A negative correlation was found between mRNFLT, RNFLA and age. There were significant differences in most parameters among three groups with different disc size, such as CA, C/DAR, CV, RA and CSM, but not in mRNFLT, RNFLA and RV.
Significant variations were found in parameters of ONH in normal subjects. Some parameters of ONH were affected by age and optic disc size. There were differences in some parameters between right and left eyes, but not between different genders. There were differences of parameters between different quadrants of ONH.
研究正常受试者的视神经乳头（ONH）参数和地形图特征，并分析性别、眼别、年龄和视盘大小对视神经乳头地形图的影响。
使用海德堡视网膜断层扫描仪（HRT）获取116名正常志愿者216只眼的视神经乳头参数和地形图图像。分析性别、眼别、年龄和视盘大小对地形图的影响。根据视盘大小将视盘分为三组，小视盘（小于1.5平方毫米）、中等视盘和大视盘（等于或大于2.5平方毫米），以评估参数差异。
正常眼的视神经乳头参数如下：视盘面积（DA）（2.208±0.411）平方毫米，杯盘面积（CA）（0.466±0.355）平方毫米，杯盘面积比（C/DAR）（0.217±0.137），盘沿面积（RA）（1.563±0.339）平方毫米，高度变化轮廓（HVC）（0.404±0.096）毫米，杯体积（CV）0.127立方毫米，盘沿体积（RV）（0.446±0.173）立方毫米，平均杯深度（MCD）（0.196±0.096）毫米，最大杯深度（MxCD）（0.559±0.228）毫米，杯形状测量值（CSM）（-0.213±0.076），平均视网膜神经纤维层厚度（mRNFLT）（0.272±0.076）毫米，以及视网膜神经纤维层横截面积（RNFLA）（1.364±0.375）平方毫米。C/DAR、RA和RV在右眼和左眼之间存在显著差异，但所有参数在不同性别之间无差异。mRNFLT、RNFLA与年龄之间存在负相关。不同视盘大小的三组之间大多数参数存在显著差异，如CA、C/DAR、CV、RA和CSM，但mRNFLT、RNFLA和RV无差异。
正常受试者的视神经乳头参数存在显著差异。视神经乳头的一些参数受年龄和视盘大小影响。右眼和左眼在一些参数上存在差异，但不同性别之间无差异。视神经乳头不同象限之间的参数存在差异。
