人类连接组：人类大脑的结构描述。
The human connectome: A structural description of the human brain.
作者信息
Sporns Olaf, Tononi Giulio, Kötter Rolf
机构信息
Department of Psychology, Indiana University, Bloomington, Indiana, United States of America.
出版信息
PLoS Comput Biol. 2005 Sep;1(4):e42. doi: 10.1371/journal.pcbi.0010042.
Abstract
The connection matrix of the human brain (the human "connectome") represents an indispensable foundation for basic and applied neurobiological research. However, the network of anatomical connections linking the neuronal elements of the human brain is still largely unknown. While some databases or collations of large-scale anatomical connection patterns exist for other mammalian species, there is currently no connection matrix of the human brain, nor is there a coordinated research effort to collect, archive, and disseminate this important information. We propose a research strategy to achieve this goal, and discuss its potential impact.
摘要
人类大脑的连接矩阵（人类“连接组”）是基础和应用神经生物学研究不可或缺的基础。然而，连接人类大脑神经元成分的解剖学连接网络在很大程度上仍然未知。虽然其他哺乳动物物种存在一些大规模解剖学连接模式的数据库或汇编，但目前尚无人类大脑的连接矩阵，也没有协调一致的研究工作来收集、存档和传播这一重要信息。我们提出了一项实现这一目标的研究策略，并讨论了其潜在影响。
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