Ieda Teruyo, Horii Yuichi, Petrick Gert, Yamashita Nobuyoshi, Ochiai Nobuo, Kannan Kurunthachalam
Gerstel K.K, 2-13-18, Nakane, Meguro-ku, Tokyo 152-0031, Japan.
Environ Sci Technol. 2005 Sep 15;39(18):7202-7. doi: 10.1021/es050568d.
Nonylphenol (NP) is a degradation product of nonylphenol polyethoxylate surfactants and has been reported to occur in water and sediments from urban areas. Technical NP is composed of several structural isomers, and conventional gas chromatography-mass spectrometry techniques have tentatively identified up to 22 components. Isolation and characterization of individual isomers in a technical NP mixture is important, because of the differences in estrogenic and bioaccumulation potential among the isomers. In this study, comprehensive two-dimensional gas chromatography (GC x GC) combined with mass spectrometry (MS) enabled tentative identification of 102 components of NP from a technical mixture. GC x GC-MS was also used to quantify two NP isomers in river water samples. This is the first study to use GC x GC-MS to characterize NP isomers in technical mixtures and for quantitative analysis of NP in river waters.
壬基酚（NP）是壬基酚聚乙氧基化物表面活性剂的降解产物，据报道在城市地区的水和沉积物中存在。工业用壬基酚由几种结构异构体组成，传统的气相色谱 - 质谱技术已初步鉴定出多达22种成分。由于异构体之间在雌激素活性和生物累积潜力方面存在差异，因此分离和表征工业用壬基酚混合物中的各个异构体很重要。在本研究中，综合二维气相色谱（GC×GC）与质谱（MS）联用能够初步鉴定出工业用混合物中102种壬基酚成分。GC×GC - MS还用于定量分析河水样品中的两种壬基酚异构体。这是首次使用GC×GC - MS来表征工业用混合物中的壬基酚异构体并对河水中的壬基酚进行定量分析的研究。
