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Equine and canine Anaplasma phagocytophilum strains isolated on the island of Sardinia (Italy) are phylogenetically related to pathogenic strains from the United States.在撒丁岛（意大利）分离出的马和犬嗜吞噬细胞无形体菌株在系统发育上与来自美国的致病菌株相关。
Appl Environ Microbiol. 2005 Oct;71(10):6418-22. doi: 10.1128/AEM.71.10.6418-6422.2005.
2
Molecular diagnosis of granulocytic anaplasmosis and infectious cyclic thrombocytopenia by PCR-RFLP.通过聚合酶链反应-限制性片段长度多态性技术对粒细胞无形体病和感染性循环性血小板减少症进行分子诊断。
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3
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4
The dusky-footed woodrat (Neotoma fuscipes) is susceptible to infection by Anaplasma phagocytophilum originating from woodrats, horses, and dogs.暗足林鼠（Neotoma fuscipes）易受源自林鼠、马和狗的嗜吞噬细胞无形体感染。
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Vector Borne Zoonotic Dis. 2011 Oct;11(10):1391-3. doi: 10.1089/vbz.2010.0251. Epub 2011 Sep 16.

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本文引用的文献

1
MEGA3: Integrated software for Molecular Evolutionary Genetics Analysis and sequence alignment.MEGA3：用于分子进化遗传学分析和序列比对的集成软件。
Brief Bioinform. 2004 Jun;5(2):150-63. doi: 10.1093/bib/5.2.150.
2
First molecular characterization of a granulocytic Ehrlichia strain isolated from a dog in South Italy.从意大利南部一只狗身上分离出的粒细胞埃立克体菌株的首次分子特征分析。
Vet J. 2004 May;167(3):224-7. doi: 10.1016/j.tvjl.2004.02.008.
3
High diversity of ankA sequences of Anaplasma phagocytophilum among Ixodes ricinus ticks in Germany.德国蓖麻硬蜱中嗜吞噬细胞无形体ankA序列的高度多样性。
J Clin Microbiol. 2003 Nov;41(11):5033-40. doi: 10.1128/JCM.41.11.5033-5040.2003.
4
Human granulocytic ehrlichiosis in Italy: first report on two confirmed cases.意大利的人粒细胞埃立克体病：两例确诊病例的首次报告。
Ann N Y Acad Sci. 2003 Jun;990:350-2. doi: 10.1111/j.1749-6632.2003.tb07387.x.
5
Genetic diversity of bacterial agents detected in ticks removed from asymptomatic patients in northeastern Italy.在意大利东北部无症状患者身上采集的蜱虫中检测到的细菌病原体的遗传多样性。
Ann N Y Acad Sci. 2003 Jun;990:182-90. doi: 10.1111/j.1749-6632.2003.tb07360.x.
6
Canine granulocytic ehrlichiosis (CGE) in Italy.意大利的犬粒细胞埃立克体病（CGE）。
Acta Vet Hung. 2003;51(1):73-90. doi: 10.1556/avet.51.2003.1.7.
7
Comparison of PCR assays for detection of the agent of human granulocytic ehrlichiosis, Anaplasma phagocytophilum.用于检测人粒细胞埃立克体病病原体嗜吞噬细胞无形体的聚合酶链反应检测方法比较
J Clin Microbiol. 2003 Feb;41(2):717-22. doi: 10.1128/JCM.41.2.717-722.2003.
8
Human granulocytic ehrlichiosis in Europe.欧洲的人类粒细胞埃立克体病
Clin Microbiol Infect. 2002 Dec;8(12):763-72. doi: 10.1046/j.1469-0691.2002.00557.x.
9
Infection with Anaplasma phagocytophila in cervids from Slovenia: evidence of two genotypic lineages.斯洛文尼亚鹿类动物感染嗜吞噬细胞无形体：两个基因型谱系的证据
Wien Klin Wochenschr. 2002 Jul 31;114(13-14):641-7.
10
Reorganization of genera in the families Rickettsiaceae and Anaplasmataceae in the order Rickettsiales: unification of some species of Ehrlichia with Anaplasma, Cowdria with Ehrlichia and Ehrlichia with Neorickettsia, descriptions of six new species combinations and designation of Ehrlichia equi and 'HGE agent' as subjective synonyms of Ehrlichia phagocytophila.立克次氏体目里克次体科和无形体科属的重新分类：将埃立克体属的一些物种与无形体属合并、考德里体属与埃立克体属合并以及埃立克体属与新立克次体属合并，六个新物种组合的描述以及将马埃立克体和“人粒细胞埃立克体病病原体”指定为嗜吞噬细胞埃立克体的主观同义词。
Int J Syst Evol Microbiol. 2001 Nov;51(Pt 6):2145-2165. doi: 10.1099/00207713-51-6-2145.

在撒丁岛（意大利）分离出的马和犬嗜吞噬细胞无形体菌株在系统发育上与来自美国的致病菌株相关。

Equine and canine Anaplasma phagocytophilum strains isolated on the island of Sardinia (Italy) are phylogenetically related to pathogenic strains from the United States.

作者信息

Alberti Alberto, Zobba Rosanna, Chessa Bernardo, Addis Maria Filippa, Sparagano Olivier, Pinna Parpaglia Maria Luisa, Cubeddu Tiziana, Pintori Gianpaolo, Pittau Marco

机构信息

Istituto di Patologia Speciale e Clinica Medica Veterinaria, Università degli Studi di Sassari, Via Vienna 2, 07100 Sassari, Italy.

出版信息

Appl Environ Microbiol. 2005 Oct;71(10):6418-22. doi: 10.1128/AEM.71.10.6418-6422.2005.

DOI:10.1128/AEM.71.10.6418-6422.2005
PMID:16204571
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1265917/
Abstract

The presence of Anaplasma phagocytophilum, a tick-transmitted zoonotic pathogen, was investigated in Sardinia using a molecular approach. Phylogenetic analysis revealed that Sardinian strains are genetically distinct from the two lineages previously described in Europe and are closely related to strains isolated in different areas of the United States.

摘要

利用分子方法，对撒丁岛蜱传播的人畜共患病原体嗜吞噬细胞无形体的存在情况进行了调查。系统发育分析表明，撒丁岛菌株在基因上与欧洲先前描述的两个谱系不同，并且与在美国不同地区分离出的菌株密切相关。