Zehetgruber Harald, Bittner Barbara, Gruber Diego, Krepler Petra, Trieb Klemens, Kotz Rainer, Dominkus Martin
Department of Orthopedics, University Hospital Vienna, Vienna, Austria.
Clin Orthop Relat Res. 2005 Oct;439:136-43. doi: 10.1097/01.blo.0000173256.85016.c4.
Aneurysmal and solitary bone cysts develop most commonly during skeletal growth. The objective of our epidemiologic study was to evaluate the prevalence, recurrence rate, and probability of recurrence-free survival for aneurysmal and solitary bone cysts in young patients. We did a population-based analysis of 141 histologically confirmed cases. Seventy-three patients with aneurysmal bone cysts and 68 patients with solitary bone cysts were registered. The annual prevalence was 0.32 per 100,000 individuals (range, 0-1.238) for aneurysmal cysts, with a 1.8:1 male to female ratio and a median age of the patients of 11.1 years (range, 1-19.7 years). For solitary bone cysts, the calculated annual prevalence was 0.30 (range, 0-0.963) with a median age of the patients of 1.1 years (range, 0.5-19.9) and a 1.96:1 male to female ratio. Recurrent lesions occurred frequently in young males. Secondary aneurysmal bone cysts were observed only in females. During skeletal growth, aneurysmal and juvenile bone cysts more often occur in males with a peak prevalence at approximately 11 years of age. A greater prevalence of aneurysmal bone cysts in young individuals is associated with skeletal growth and immaturity. Young age and male gender are associated with an increased risk of local recurrence.
动脉瘤样骨囊肿和孤立性骨囊肿最常见于骨骼生长期间。我们的流行病学研究目的是评估年轻患者中动脉瘤样骨囊肿和孤立性骨囊肿的患病率、复发率及无复发生存概率。我们对141例经组织学确诊的病例进行了基于人群的分析。登记了73例动脉瘤样骨囊肿患者和68例孤立性骨囊肿患者。动脉瘤样囊肿的年患病率为每10万人0.32（范围0 - 1.238），男女比例为1.8:1，患者中位年龄为11.1岁（范围1 - 19.7岁）。对于孤立性骨囊肿，计算出的年患病率为0.30（范围0 - 0.963），患者中位年龄为1.1岁（范围0.5 - 19.9），男女比例为1.96:1。复发性病变在年轻男性中频繁发生。继发性动脉瘤样骨囊肿仅在女性中观察到。在骨骼生长期间，动脉瘤样骨囊肿和青少年骨囊肿更常发生于男性，患病率高峰约在11岁。年轻个体中动脉瘤样骨囊肿患病率较高与骨骼生长和不成熟有关。年轻和男性性别与局部复发风险增加有关。
