Systems biology approaches in cell signaling research.

作者信息

Chen Raymond E, Thorner Jeremy

机构信息

Division of Biochemistry and Molecular Biology, Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720-3202, USA.

出版信息

Genome Biol. 2005;6(10):235. doi: 10.1186/gb-2005-6-10-235. Epub 2005 Sep 29.

DOI:10.1186/gb-2005-6-10-235

PMID:16207364

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1257459/

Abstract

The use of methods for global and quantitative analysis of cells is providing new systems-level insights into signal transduction processes. Recent studies reveal important information about the rates of signal transmission and propagation, help establish some general regulatory characteristics of multi-tiered signaling cascades, and illuminate the combinatorial nature of signaling specificity in cell differentiation.

摘要