Gioseffi O N, Alfonso G, Rosenfeld E, Briend S, Cohen R
Hospital Nacional Profesor Alejandro Posadas, Servicio de Hematología, Buenos Aíres, Republica Argentina.
Sangre (Barc). 1992 Apr;37(2):137-9.
The case of a 36-year old man with IgA kappa multiple myeloma in whom meningeal myelomatosis developed is reported, and a brief review of previously published cases is made. Meningeal involvement develops in patients with high tumoral mass myeloma. Because of its poor prognosis, central nervous system chemoprophylaxis based on clinical and cerebrospinal fluid data, and systemic treatment according to severity, is suggested.
报告了一例36岁的IgA κ型多发性骨髓瘤患者发生脑膜骨髓瘤病的病例，并对先前发表的病例进行了简要回顾。脑膜受累在高肿瘤负荷的骨髓瘤患者中出现。鉴于其预后较差，建议根据临床和脑脊液数据进行中枢神经系统化学预防，并根据严重程度进行全身治疗。
