Department of Haematology, King Khalid National Guard Hospital, Jeddah, Saudi Arabia.
East Mediterr Health J. 2009 Nov-Dec;15(6):1570-9.
Multiple myeloma (MM) is a systemic malignancy of pathologic plasma cells that is treatable with chemotherapeutic agents and irradiation, but rarely curable. The spectrum of neurological complications of MM is diverse; however, involvement of MM in the cerebrospinal fluid and leptomeningeal infiltration is considered rare. There have been many reviews of central nervous system complications in MM but there are none on intracranial and leptomeningeal infiltration of MM. We review this here along with our clinicopathological experience and a summary of our present knowledge of this condition.
多发性骨髓瘤（MM）是一种病理性浆细胞的系统性恶性肿瘤，可通过化疗药物和放疗治疗，但很少能治愈。MM 的神经并发症谱多种多样；然而，MM 累及脑脊液和软脑膜浸润被认为很少见。已有许多关于 MM 的中枢神经系统并发症的综述，但没有关于 MM 的颅内和软脑膜浸润的综述。我们在这里回顾了这一点，以及我们的临床病理经验，并总结了我们目前对这种疾病的认识。
