Korinek A, Solal-Celigny P, Kuentz M, Farcet J P, Clauvel J P
Presse Med. 1985 Mar 30;14(13):733-6.
Meningeal involvement is extremely rare in multiple myeloma. Its characteristic features can be derived from the 3 cases presented here and from the 11 cases previously published. Specific signs of meningeal myelomatosis include convulsions, confusion, cranial nerve palsies and plasma cells in the cerebrospinal fluid. Meningitis develops in patients with high tumoral mass myeloma, leukaemic in one-half of the cases. Treatment is ineffective, and death occurs within a few months.
脑膜受累在多发性骨髓瘤中极为罕见。其特征可从此处呈现的3例病例以及先前发表的11例病例中得出。脑膜骨髓瘤病的特定体征包括惊厥、意识模糊、颅神经麻痹以及脑脊液中的浆细胞。脑膜炎在高肿瘤负荷骨髓瘤患者中发生,其中一半病例为白血病性。治疗无效,患者在数月内死亡。