Schlegel Peter N, Paduch Darius A
Department of Urology, Weill Medical College, Cornell University, New York, New York 10021, USA.
Fertil Steril. 2005 Oct;84(4):854-9. doi: 10.1016/j.fertnstert.2005.04.050.
Sperm chromatin can affect reproductive performance, and it may be analyzed by measuring susceptibility of DNA to breakage using assays such as the sperm chromatin structure assay, comet assay, TUNEL, and DNA ladders. The newly proposed test, Halosperm, may not provide additional information beyond that obtained with existent evaluations.
精子染色质会影响生殖性能,可通过使用诸如精子染色质结构分析、彗星试验、末端脱氧核苷酸转移酶介导的缺口末端标记法(TUNEL)和DNA梯状条带分析等检测方法测量DNA对断裂的敏感性来进行分析。新提出的Halosperm检测可能无法提供超出现有评估所获得的额外信息。