Orthotopic transplantation of fresh ovarian cortex: a report of two cases.

作者信息

Donnez Jacques, Squifflet Jean, Dolmans Marie-Madeleine, Martinez-Madrid Belen, Jadoul Pascale, Van Langendonckt Anne

机构信息

Department of Gynecology, Université Catholique de Louvain, Cliniques Universitaires Saint-Luc, Brussels, Belgium.

出版信息

Fertil Steril. 2005 Oct;84(4):1018. doi: 10.1016/j.fertnstert.2005.06.011.

OBJECTIVE

To report two cases of orthotopic transplantation of fresh ovarian tissue.

SETTING

Academic hospital.

PATIENT(S): Two patients with severe endometriosis, who underwent left oophorectomy for recurrent endometriosis.

INTERVENTION(S): Ovarian cortex was reimplanted in the heterolateral orthotopic site.

RESULT(S): Biopsies of the grafted tissue were taken 3 months after reimplantation. Viable primordial follicles were found. The presence of a neovascular capillary network was demonstrated.

CONCLUSION(S): Reimplantation of fresh ovarian cortex allows the survival of primordial follicles and may represent an alternative method for the preservation of ovarian cortex when oophorectomy is mandatory.