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一份骨质疏松症问卷的无用性及骨量测量在预测牙齿脱落中的作用

Uselessness of a questionnaire for osteoporosis and role of bone mass measurements in predicting tooth loss.

作者信息

Vescini F, Morselli Labate A M, Buffa A, Ripani R, Caudarella R

机构信息

Department of Clinical Medicine and Applied Biotechnology D. Campanacci, Alma Mater Studiorum, University of Bologna, Bologna, Italy.

出版信息

Minerva Stomatol. 2005 Sep;54(9):497-507.

PMID:16215534
Abstract

AIM

We evaluated whether the number of teeth lost is associated with risk factors for osteoporosis and whether bone mass measurements can add further information.

METHODS

A total of 455 healthy women were enrolled. All the subjects filled in a questionnaire on risk factors for osteoporosis. The bone mineral density (BMD) was measured both by dual X-ray absorptiometry (DXA) and quantitative ultrasound measurements (QUS).

RESULTS

On the basis of the questionnaire score 65.1% of the subjects were in the low risk category, 11% in the moderate risk category, 19.3% in the fairly high risk category and 4.6% in the high risk category. Close relationships (P<0.001) were observed between bone mass loss and the questionnaire risk categories. The number of teeth lost significantly increased from normal to osteoporosis groups. High correlations were also found between osteosonographic parameters and the number of teeth lost. Among questionnaire items a significant positive correlation was found only between the number of teeth lost and both age class (P<0.001) and years since menopause (P<0.001). A multiple regression showed that only age class (P<0.001) and ultrasound bone profile index (UBPI) (P=0.041) were independently linked to tooth loss.

CONCLUSIONS

The results obtained showed that age is the main determinant of tooth loss and that QUS adds further information in identifying patients at a higher risk of tooth loss.

摘要

目的

我们评估了牙齿缺失数量是否与骨质疏松症的危险因素相关,以及骨量测量是否能提供更多信息。

方法

共纳入455名健康女性。所有受试者填写了一份关于骨质疏松症危险因素的问卷。通过双能X线吸收法(DXA)和定量超声测量(QUS)测量骨密度(BMD)。

结果

根据问卷评分,65.1%的受试者属于低风险类别,11%属于中度风险类别,19.3%属于较高风险类别,4.6%属于高风险类别。观察到骨量丢失与问卷风险类别之间存在密切关系(P<0.001)。从正常组到骨质疏松组,牙齿缺失数量显著增加。骨超声参数与牙齿缺失数量之间也发现高度相关性。在问卷项目中,仅在牙齿缺失数量与年龄组(P<0.001)和绝经年限(P<0.001)之间发现显著正相关。多元回归显示,只有年龄组(P<0.001)和超声骨轮廓指数(UBPI)(P=0.041)与牙齿缺失独立相关。

结论

所得结果表明年龄是牙齿缺失的主要决定因素,并且QUS在识别牙齿缺失风险较高的患者方面提供了更多信息。

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