Agarwal H C, Poovali S, Sihota R, Dada T
Glaucoma Research Laboratory, Dr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.
Eye (Lond). 2006 Dec;20(12):1352-6. doi: 10.1038/sj.eye.6702108. Epub 2005 Oct 7.
To evaluate the efficacy of diode laser trabeculoplasty (DLT) and frequency doubled Nd : YAG laser trabeculoplasty (YLT) in primary open angle glaucoma (POAG).
A total of 52 eyes of 35 patients with POAG were included. In all, 25 eyes underwent DLT (Group I) and 27 eyes underwent YLT (Group II). IOP, gonioscopy and visual fields were evaluated before and 3, 6, and 9 months and 1 year after the laser. An IOP<21 mmHg without medications or a decrease in the number of glaucoma medications with no progression of disc and field changes was considered a success.
The mean age of patients in Group I was 57.72+/-8.1 years and the patients in Group II had a mean age of 59.85+/-7.76 years. The mean prelaser IOP was 24.93+/-1.49 mmHg and 25.36+/-1.57 mmHg. The mean IOP after DLT at 12 months follow-up was 18.0+/-0.93 mmHg and after YLT was 18.6+/-1.52 mmHg. The reduction of IOP was statistically significant in both the groups at 3, 6, 9, and 12 months (P<0.001), however there was no significant difference between the two groups. Success rates in both groups were similar, 92% in Group I and 92.6% in Group II.
DLT and Fd YLT are equally effective in controlling IOP in eyes with POAG.
评估二极管激光小梁成形术（DLT）和倍频Nd:YAG激光小梁成形术（YLT）治疗原发性开角型青光眼（POAG）的疗效。
纳入35例POAG患者的52只眼。其中，25只眼接受DLT治疗（第一组），27只眼接受YLT治疗（第二组）。在激光治疗前以及治疗后3个月、6个月、9个月和1年评估眼压、前房角镜检查和视野。眼压<21 mmHg且无需药物治疗，或青光眼药物数量减少且视盘和视野无进展被视为治疗成功。
第一组患者的平均年龄为57.72±8.1岁，第二组患者的平均年龄为59.85±7.76岁。激光治疗前的平均眼压分别为24.93±1.49 mmHg和25.36±1.57 mmHg。DLT治疗后12个月随访时的平均眼压为18.0±0.93 mmHg，YLT治疗后为18.6±1.52 mmHg。两组在3个月、6个月、9个月和12个月时眼压降低均具有统计学意义（P<0.001），但两组之间无显著差异。两组的成功率相似，第一组为92%，第二组为92.6%。
DLT和倍频YLT在控制POAG患者眼压方面同样有效。
