Mahar P S, Jamali K K
Department of Ophthalmology, Isra Postgraduate Centre, Malir, Karachi.
J Coll Physicians Surg Pak. 2008 Feb;18(2):102-4.
To determine the effect of Argon Laser Trabeculoplasty (ALT) as a primary mode of therapy in reducing the intraocular Pressure (IOP) of patients diagnosed with Primary Open Angle Glaucoma (POAG).
Quasi experimental study.
The study was carried out at Isra Postgraduate Institute of Ophthalmology, Karachi, from July 2003 to July 2004.
A total of 35 eyes of 35 patients with the gender distribution of 27 men and 8 women who were newly diagnosed with POAG, were included in this study. Mean age of the patients was 55.2 years with the range of 32 to 76 years. All of them were treated with argon laser trabeculoplasty as a primary mode of therapy. Intra ocular pressure was measured objectively using Goldman applanation tonometer, pre-and-post laser therapy.
The pre-laser mean IOP was 27.63 mmHg (range 21-40 mmHg). The post-laser mean IOP measured at 6 months follow up was 15.5 mmHg (range 11 - 33 mmHg) with mean decrease of 12.1 mmHg. The decrease in IOP was seen in 32 eyes (95%) with no change observed in 3 (5%) eyes.
The result shows a marked decline in IOP in patients with POAG who underwent ALT as a primary mode of treatment. Further studies with large sample size and longer follow-up will help in making future recommendations.
确定氩激光小梁成形术(ALT)作为主要治疗方式对降低原发性开角型青光眼(POAG)患者眼压(IOP)的效果。
准实验研究。
该研究于2003年7月至2004年7月在卡拉奇的伊斯雷眼科研究生学院进行。
本研究纳入了35例新诊断为POAG的患者的35只眼,性别分布为男性27例,女性8例。患者的平均年龄为55.2岁,年龄范围为32至76岁。所有患者均接受氩激光小梁成形术作为主要治疗方式。在激光治疗前后,使用戈德曼压平眼压计客观测量眼压。
激光治疗前平均眼压为27.63 mmHg(范围21 - 40 mmHg)。6个月随访时测量的激光治疗后平均眼压为15.5 mmHg(范围11 - 33 mmHg),平均降低12.1 mmHg。32只眼(95%)眼压降低,3只眼(5%)未见变化。
结果显示,接受ALT作为主要治疗方式的POAG患者眼压显著下降。进一步开展大样本量和更长随访时间的研究将有助于做出未来的建议。