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[猴眼二极管激光眼内光凝病变视网膜脉络膜粘连的组织病理学]

[Histopathology of retinochoroidal adhesions of diode laser endophotocoagulation lesions in monkey eyes].

作者信息

Aso S

机构信息

Department of Ophthalmology, Nihon University School of Medicine, Chiyoda-ku, Japan.

出版信息

Nippon Ganka Gakkai Zasshi. 1992 May;96(5):620-7.

PMID:1621607
Abstract

Retinochoroidal coagulation effect of 810 nm diode laser was studied using monkey eyes to determine the energy necessary to produce retinochoroidal adhesion safely. Power settings were at 100, 200 and 300 mW. The lesions produced with a power of 100 mW were faint grayish spots. One month after photocoagulation, there was degeneration from the outer granular layer to the superficial choroidal layer. However, chorioretinal adhesion was not obtained due to external limiting membrane formation. The lesions produced with a power of 200 mW were characterized by small whitish spots surrounded by grayish rings and retinochoroidal adhesions were produced by proliferated cells. However choroid were intensely coagulated, and there was a rupture of Bruch's membrane in one lesion. The lesions produced with a power of 300 mW were intense white spots surrounded by grayish rings. Histologically, severe cell loss of the retina was seen and three was no retinochoroidal adhesion. It can be said that it is difficult for 810 nm diode laser to obtain adequate retinochoroidal adhesion safely.

摘要

使用猴眼研究了810纳米二极管激光的视网膜脉络膜凝固效应,以确定安全产生视网膜脉络膜粘连所需的能量。功率设置为100、200和300毫瓦。100毫瓦功率产生的病变为淡灰色斑点。光凝后1个月,从外颗粒层到脉络膜浅层出现变性。然而,由于外部限制膜的形成,未获得脉络膜视网膜粘连。200毫瓦功率产生的病变表现为白色小斑点周围有灰色环,增殖细胞产生脉络膜视网膜粘连。然而脉络膜被强烈凝固,一个病变中出现了布鲁赫膜破裂。300毫瓦功率产生的病变为强烈的白色斑点周围有灰色环。组织学上,可见视网膜严重细胞丢失,未出现脉络膜视网膜粘连。可以说,810纳米二极管激光很难安全地获得足够的脉络膜视网膜粘连。

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