Okuyama M, Okisaka S, Nakagami T, Sai Y, Mizukawa A, Ito M, Ohta Y
Department of Ophthalmology, National Defense Medical College, Saitama-ken, Japan.
Nippon Ganka Gakkai Zasshi. 1996 Sep;100(9):692-7.
A histopathological study of macaca monkey retina-choroid was carried out for one month after mild photocoagulation with a diode laser (680 nm) and a krypton laser (647 nm). Both lasers produced the same damage to the outer layer of retina and to the melanocytes of 1/3 of the inner choroid. Mild focal photocoagulation was done for 6 patients (12 eyes) with diabetic maculopathy. The patients were 41 to 67 years old, suffering from diabetes mellitus for 5 to 25 years. The grade of their retinopathy was Fukuda's classification AI, AII, and BI. AII eyes were tested before and 3-6 months after photocoagulation for corrected visual acuity, fluorescein angiography, and visual field sensitivity by Octopus automated static perimetry. Visual acuity was stable in all cases. Central sensitivity was better in 2 eyes and unchanged in 4 eyes in both types of laser photocoagulation. In cases of total loss, one eye was improved, 4 eyes were unchanged and one eye was worsened by diode laser photocoagulation and one eye was improved, 2 eyes were unchanged and 3 eyes were worsened by krypton laser photocoagulation. The diode laser (680 nm) might be as useful for ophthalmic laser treatment as the krypton laser.
用二极管激光(680纳米)和氪激光(647纳米)进行轻度光凝后,对猕猴视网膜-脉络膜进行了为期一个月的组织病理学研究。两种激光对视网膜外层和内脉络膜三分之一的黑素细胞造成的损伤相同。对6例(12只眼)糖尿病性黄斑病变患者进行了轻度局灶性光凝。患者年龄在41至67岁之间,患糖尿病5至25年。其视网膜病变分级为福田分类AI、AII和BI。对AII级眼在光凝前以及光凝后3至6个月进行了矫正视力、荧光素血管造影和用Octopus自动静态视野计进行视野敏感度检测。所有病例的视力均稳定。两种激光光凝中,2只眼的中心敏感度提高,4只眼不变。在完全丧失的病例中,二极管激光光凝后1只眼改善,4只眼不变,1只眼恶化;氪激光光凝后1只眼改善,2只眼不变,3只眼恶化。二极管激光(680纳米)在眼科激光治疗中可能与氪激光一样有用。