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输血相关性急性肺损伤

Transfusion-related acute lung injury.

作者信息

Webert Kathryn E, Blajchman Morris A

机构信息

Department of Medicine, McMaster University, Hamilton, Ontario, Canada.

出版信息

Curr Opin Hematol. 2005 Nov;12(6):480-7. doi: 10.1097/01.moh.0000177829.85904.39.

DOI:10.1097/01.moh.0000177829.85904.39
PMID:16217166
Abstract

PURPOSE OF REVIEW

Transfusion-related acute lung injury is an uncommon complication of blood transfusion typically manifested by shortness of breath, fever, and hypotension. Transfusion-related acute lung injury is an important cause of transfusion-related morbidity and mortality.

RECENT FINDINGS

Much about the pathogenesis, treatment, and prevention of transfusion-related acute lung injury is poorly understood or is controversial. There is increasing recognition that transfusion-related acute lung injury is an important clinical syndrome, causing most transfusion-related deaths.

SUMMARY

In this report, what is known about transfusion-related acute lung injury is summarized with particular emphasis on recent studies. Some of the areas in which knowledge and/or consensus are currently lacking are identified.

摘要

综述目的

输血相关急性肺损伤是输血的一种罕见并发症，通常表现为呼吸急促、发热和低血压。它是输血相关发病和死亡的重要原因。

最新发现

关于输血相关急性肺损伤的发病机制、治疗和预防，目前仍知之甚少或存在争议。人们越来越认识到输血相关急性肺损伤是一种重要的临床综合征，导致了大多数输血相关死亡。

总结

在本报告中，总结了关于输血相关急性肺损伤的已知情况，特别强调了近期研究。还指出了目前知识和/或共识尚缺的一些领域。

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