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自膨式金属支架缓解恶性胃出口梗阻

Palliation of malignant gastric outlet obstruction with self-expanding metal stents.

作者信息

Feretis C, Benakis P, Dimopoulos C, Georgopoulos K, Milas F, Manouras A, Apostolidis N

机构信息

Dept. of Surgical Endoscopy, Hygeia Diagnostic and Therapeutic Center, Athens, Greece.

出版信息

Endoscopy. 1996 Feb;28(2):225-8. doi: 10.1055/s-2007-1005432.

DOI:10.1055/s-2007-1005432
PMID:8739737
Abstract

BACKGROUND AND STUDY AIMS

Self-expanding metal stents have long been used in the management of patients with malignant esophageal and malignant biliary obstruction. The aim of the present study was to report on the palliation of malignant gastric outlet obstruction using self-expanding endoprostheses.

PATIENTS AND METHODS

Between March 1993 and December 1994, 12 patients (eight women, four men, mean age 64 years) suffering from malignant gastric outlet obstruction due to recurrent gastric carcinoma (seven patients) and pancreatic head carcinoma (five patients) presented with an inability to eat and intractable vomiting. The patients were managed with peroral insertion of self-expanding metal stents.

RESULTS

Peroral introduction of the stent with the aid of a stabilizing overtube was successful in all patients, with the stent being supported as it was being advanced through the stenosis. Proper release of the stent into the stenotic area was achieved in all cases, relieving the intractable vomiting. The procedure was accomplished without any complications. All patients were able to eat semisolid food four days after the stent insertion. Apart from an asymptomatic partial stent occlusion in one patient, no other complications were seen during the short-term follow-up one, two, and three months after discharge.

CONCLUSIONS

These preliminary results suggest that self-expanding stents can effectively relieve malignant gastric outlet obstruction.

摘要

背景与研究目的

自膨式金属支架长期以来一直用于治疗恶性食管梗阻和恶性胆管梗阻患者。本研究的目的是报告使用自膨式内置假体缓解恶性胃出口梗阻的情况。

患者与方法

1993年3月至1994年12月期间,12例患者(8名女性,4名男性,平均年龄64岁)因复发性胃癌(7例)和胰头癌(5例)导致恶性胃出口梗阻,出现无法进食和顽固性呕吐。对这些患者采用经口插入自膨式金属支架进行治疗。

结果

在稳定外套管的辅助下,所有患者经口置入支架均获成功,支架在通过狭窄部位时得到支撑。所有病例中支架均成功释放至狭窄区域,顽固性呕吐得以缓解。该操作未出现任何并发症。所有患者在支架置入4天后均能进食半固体食物。除1例患者出现无症状的部分支架堵塞外,出院后1个月、2个月和3个月的短期随访期间未发现其他并发症。

结论

这些初步结果表明,自膨式支架可有效缓解恶性胃出口梗阻。

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