Parmeggiani A, Posar A, Leonardi M, Rossi P G
Department of Child Neurology and Psychiatry, University of Bologna, Italy.
Brain Dev. 1992 Mar;14(2):107-9. doi: 10.1016/s0387-7604(12)80096-9.
A case is described of congenital bilateral ptosis and ophthalmoplegia due to incomplete bilateral paralysis of the third cranial nerve associated with dysmorphisms, brain malformations and epileptiform EEG abnormalities. We hypothesize that in our case the ophthalmological disturbance is due to mesencephalic impairment. In literature there are few reports of congenital bilateral paralysis of the third cranial nerve and they lack detailed MRI findings. We stress in patients with congenital third cranial nerve palsy the importance of thorough neurological investigations including prolonged wake-sleep EEG monitoring as well as CT scan and MRI to establish the origin of the disorder.
本文描述了一例因双侧第三脑神经不完全麻痹导致的先天性双侧上睑下垂和眼肌麻痹病例，该病例伴有畸形、脑畸形和癫痫样脑电图异常。我们推测，在我们的病例中，眼科疾病是由于中脑损伤所致。文献中关于先天性双侧第三脑神经麻痹的报道很少，且缺乏详细的MRI检查结果。我们强调，对于先天性第三脑神经麻痹患者，进行全面的神经学检查非常重要，包括长时间的清醒-睡眠脑电图监测以及CT扫描和MRI检查，以确定疾病的起源。
