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[双侧睑下垂伴单侧上视麻痹:一例报告]

[Bilateral palpebral ptosis with unilateral paralysis of upward gaze: a case report].

作者信息

Brasil Neto J P, Tosta E D, Henriques F G

出版信息

Arq Neuropsiquiatr. 1986 Mar;44(1):82-8. doi: 10.1590/s0004-282x1986000100012.

Abstract

The authors report a case of bilateral ptosis with miosis, paralysis of upward gaze and of smooth pursuit movements to the right, as well as a slowly regressive state of lassitude. This syndrome followed a haemorrhagic brain stem infarction. After a review of the pathophysiology of ptosis and of vertical eye movements, together with analysis of data provided by computerized tomography studies--since the case was not fatal--explanations are offered for each clinical sign and it is proposed that the lesion, a paramedian, slightly deviated to the right haemorrhagic focus in the midbrain, with a diameter of 15 mm, might have involved several structures, namely the rostral interstitial nucleus of the medial longitudinal fasciculus, the mesencephalic reticular formation, as well as cortico-nuclear and sympathetic pathways.

摘要

作者报告了一例双侧上睑下垂伴瞳孔缩小、向上凝视麻痹及向右平稳跟踪运动麻痹,以及缓慢进展的倦怠状态的病例。该综合征继发于脑干出血性梗死。在回顾了上睑下垂和垂直眼球运动的病理生理学,并分析了计算机断层扫描研究提供的数据后(由于该病例未致命),对每个临床体征进行了解释,并提出病变为中脑右侧稍偏离中线的旁正中出血灶,直径为15毫米,可能累及了几个结构,即内侧纵束的嘴侧间质核、中脑网状结构以及皮质核束和交感神经通路。

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