全子宫切除术和次全子宫切除术术后下尿路症状：一项随机对照试验的结果

Lower urinary tract symptoms after total and subtotal hysterectomy: results of a randomized controlled trial.

作者信息

Gimbel Helga, Zobbe Vibeke, Andersen Birthe Jakobsen, Sørensen Helle Christina, Toftager-Larsen Kim, Sidenius Katrine, Møller Nini, Madsen Ellen Merete, Vejtorp Mogens, Clausen Helle, Rosgaard Annie, Villumsen John, Gluud Christian, Ottesen Bent S, Tabor Ann

机构信息

Department of Gynecology and Obstetrics, Roskilde County Hospital, Denmark.

出版信息

Int Urogynecol J Pelvic Floor Dysfunct. 2005 Jul-Aug;16(4):257-62. doi: 10.1007/s00192-005-1291-8.

DOI:10.1007/s00192-005-1291-8

PMID:16220584

Abstract

The aim of this Danish multicenter trial was to compare the proportion of women with lower urinary tract symptoms after total abdominal hysterectomy (TAH) and subtotal abdominal hysterectomy (SAH) for benign uterine disorders. A total of 319 women were randomized to TAH (n = 158) or SAH (n = 161). Women were followed up for 1 year by strict data collection procedures, including postal questionnaires. Results were analyzed by intention-to-treat analyses. Urinary incontinence was found less often among TAH women than among SAH women. This was due to a larger reduction of the number of women with stress and urinary incontinence in the TAH group. No other differences were found between the two operation methods. The number of women with urinary incontinence and frequency was reduced from study entry for follow-up, while double/triple voiding was increased. Incontinent women had significantly lower quality of life scores than continent women

摘要

这项丹麦多中心试验的目的是比较因良性子宫疾病接受全腹子宫切除术（TAH）和次全腹子宫切除术（SAH）的女性出现下尿路症状的比例。共有319名女性被随机分为TAH组（n = 158）或SAH组（n = 161）。通过严格的数据收集程序，包括邮寄问卷，对女性进行了1年的随访。结果采用意向性分析。发现TAH组女性尿失禁的发生率低于SAH组女性。这是由于TAH组中压力性尿失禁和尿失禁女性数量的减少幅度更大。两种手术方法之间未发现其他差异。从研究开始到随访，尿失禁和尿频的女性数量减少，而二次/三次排尿增加。失禁女性的生活质量得分明显低于非失禁女性。