Thibault Raymond J, Hotchkiss Peter J, Gray Mark, Rotello Vincent M
Department of Chemistry, University of Massachusetts, Amherst, Massachusetts, 01003, USA.
J Am Chem Soc. 2003 Sep 17;125(37):11249-52. doi: 10.1021/ja034868b.
Bis-thymine units were used to noncovalently cross-link a complementary diamidopyridine-functionalized copolymer. Upon combination in noncompetitive solvents, discrete micron-scale spherical aggregates were formed arising from specific three-point polymer-cross-linker hydrogen bonding interactions. The diameter of these microspheres could be controlled through spacer structure. The cross-linking process was fully thermally reversible, with complete dissolution observed at 50 degrees C and reformation of the aggregates upon return to ambient temperature. This process could be repeated multiply, with lower particle dispersity observed arising from the annealing process.
双胸腺嘧啶单元用于非共价交联互补的二氨基吡啶功能化共聚物。在非竞争性溶剂中混合时，由于特定的三点聚合物 - 交联剂氢键相互作用，形成了离散的微米级球形聚集体。这些微球的直径可以通过间隔结构来控制。交联过程完全是热可逆的，在50摄氏度时观察到完全溶解，回到室温时聚集体重新形成。这个过程可以多次重复，退火过程导致观察到较低的颗粒分散度。
