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褐家鼠支气管相关淋巴组织(BALT)的出生后发育

Postnatal development of bronchus-associated lymphoid tissue (BALT) in the rat, Rattus norvegicus.

作者信息

Gregson R L, Davey M J, Prentice D E

出版信息

Lab Anim. 1979 Jul;13(3):231-8. doi: 10.1258/002367779780937870.

DOI:10.1258/002367779780937870
PMID:162237
Abstract

The pattern of development of bronchus-associated lymphoid tissue (BALT) in specified-pathogen-free and conventional (non-barrier maintained) rats over the initial 4 weeks of life appeared to be similar. BALT first appeared around the 2nd week of life and increased in amount over the following 2 weeks. Overlying large nodules of BALT the bronchial epithelium becomes infiltrated by lymphocytes to form a lymphoepithelium. This transformation occurs earlier in conventional rats, possibly because of the differing antigen levels to which they are exposed.

摘要

在无特定病原体大鼠和常规(非屏障饲养)大鼠生命最初4周内,支气管相关淋巴组织(BALT)的发育模式似乎相似。BALT最早在出生后第2周左右出现,并在随后的2周内数量增加。在BALT的大结节上方,支气管上皮被淋巴细胞浸润,形成淋巴上皮。这种转变在常规大鼠中出现得更早,可能是因为它们接触的抗原水平不同。

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