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实验室饲养的野生褐家鼠(Rattus norvegicus)中的支气管相关淋巴组织(BALT)。

Bronchus-associated lymphoid tissue (BALT) in the laboratory-bred and wild rat, Rattus norvegicus.

作者信息

Gregson R L, Davey M J, Prentice D E

出版信息

Lab Anim. 1979 Jul;13(3):239-43. doi: 10.1258/002367779780937735.

DOI:10.1258/002367779780937735
PMID:162238
Abstract

In juvenile wild rats, bronchus-associated lymphoid tissue (BALT) development was similar to that seen in adult specified-pathogen-free rats. In adult wild rats the BALT was widespread. In one animal infected with a mycoplasma-like organism, a region of bronchoepithelium overlying a large BALT nodule was seen, through which lymphocytes appeared able to pass to make direct contact with the bronchial lumen: the significance of this observation is discussed. There was no evidence of infection in lungs from any of the specified-pathogen-free animals, where small foci of BALT were seen.

摘要

在幼年野生大鼠中,支气管相关淋巴组织(BALT)的发育与成年无特定病原体大鼠相似。在成年野生大鼠中,BALT分布广泛。在一只感染了支原体样生物体的动物中,观察到覆盖一个大BALT结节的支气管上皮区域,淋巴细胞似乎能够通过该区域与支气管腔直接接触:讨论了这一观察结果的意义。在任何一只无特定病原体动物的肺中均未发现感染迹象,这些动物的肺中可见小的BALT病灶。

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