血小板与血管：黏附过程
Platelets and blood vessels: the adhesion event.
作者信息
Roth G J
机构信息
Hematology Section, Seattle Veterans Hospital, WA.
出版信息
Immunol Today. 1992 Mar;13(3):100-5. doi: 10.1016/0167-5699(92)90150-6.
PMID:1622541
Abstract
Circulating blood platelets attach to damaged blood vessels by specific adhesion molecules. In the human arterial circulation, a unique 'shear-dependent' mechanism governs adhesion by a single receptor-ligand (glycoprotein Ib-von Willebrand factor) pair. Here, Gerald Roth reviews recent data that provide insights into the functions of these molecules.
摘要
循环血液中的血小板通过特定的黏附分子附着于受损血管。在人体动脉循环中，一种独特的“剪切力依赖”机制由单一的受体 - 配体（糖蛋白Ib - 血管性血友病因子）对来控制黏附。在此，杰拉尔德·罗斯回顾了近期提供这些分子功能见解的数据。
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