Luton Dominique, Le Gac Isabelle, Noel Michèle, Guibourdenche Jean, Polak Michel
Department of Perinatalogy, Multidisciplinary Centre for Prenatal Diagnosis EA3102, Robert Debré Teaching Hospital, Paris, France.
BJOG. 2005 Nov;112(11):1565-7. doi: 10.1111/j.1471-0528.2005.00736.x.
Graves' disease and thyroid dysfunction during pregnancy can lead to maternal and fetal complications. No information is available on thyroid function in women with a past history of Graves' disease. We compared free T3, free T4 and TSH in a group of pregnant women with a history of resolved Graves' disease requiring no current treatment (n= 34) and in a group of pregnant controls (n= 102). We found no significant differences in the levels of these hormones between the two groups. Women with a past history of Graves' disease and no current treatment display a normal thyroid function and adaptation during pregnancy.
格雷夫斯病及孕期甲状腺功能障碍可导致母婴并发症。目前尚无关于有格雷夫斯病病史女性甲状腺功能的信息。我们比较了一组既往有格雷夫斯病病史且目前无需治疗的孕妇(n = 34)和一组怀孕对照者(n = 102)的游离T3、游离T4和促甲状腺激素(TSH)水平。我们发现两组之间这些激素水平无显著差异。既往有格雷夫斯病病史且目前无需治疗的女性在孕期甲状腺功能及适应性表现正常。