Uemoto Riyo, Yamamoto Shuichi, Takeuchi Shinobu
Department of Ophthalmology, Yokohama City University School of Medicine, Yokohama, Japan.
Am J Ophthalmol. 2005 Oct;140(4):752-5. doi: 10.1016/j.ajo.2005.04.035.
To determine the changes in the retinal pigment epithelium (retinal pigment epithelium) and secondary changes in the choroid and fovea after indocyanine green (ICG) staining of the internal limiting lamina during surgery for an idiopathic macular hole (MH).
Observational case series.
The medical charts of 31 patients who underwent MH surgical procedures with internal limiting lamina staining and peeling were reviewed. The eyes were examined by optical coherence tomography, scanning laser ophthalmoscopy, fluorescein, and ICG angiography.
In three cases that experienced retinal pigment epithelium changes, there was foveal thinning and choriocapillary atrophy in the area of the previous MH. The visual acuity was markedly worse, and the retina was markedly thinner in these three cases than in the other cases without retinal pigment epithelium changes (P = .003, P = .009, respectively).
The use of ICG dye with illumination may increase the risk of retinal pigment epithelium damage and secondary choroidal and foveal morphologic changes.
确定在特发性黄斑裂孔（MH）手术中对内界膜进行吲哚菁绿（ICG）染色后视网膜色素上皮（视网膜色素上皮）的变化以及脉络膜和黄斑的继发性变化。
观察性病例系列。
回顾了31例行MH手术且进行内界膜染色及剥离的患者的病历。通过光学相干断层扫描、扫描激光检眼镜、荧光素和ICG血管造影对眼睛进行检查。
在3例出现视网膜色素上皮变化的病例中，先前MH区域存在黄斑变薄和脉络膜毛细血管萎缩。这3例患者的视力明显更差，视网膜也比其他未发生视网膜色素上皮变化的病例明显更薄（分别为P = 0.003，P = 0.009）。
使用ICG染料并进行照明可能会增加视网膜色素上皮损伤以及脉络膜和黄斑形态学继发性变化的风险。
