Hussain Nazimul, Jalali Subhadra, Rani Alka, Rawal Hema
Smt. Kanuri Santhamma Retina Vitreous Centre, L.V. Prasad Eye Institute, Hyderabad, India.
Indian J Ophthalmol. 2008 Sep-Oct;56(5):423-5. doi: 10.4103/0301-4738.42424.
To report subretinal migration of indocyanine green dye (ICG) and subsequent retinal pigment epithelial (RPE) atrophy during macular surgery for serous macular detachment. A 65-year-old woman presented with residual epiretinal membrane and serous detachment of the macula following vitreoretinal surgery for epiretinal membrane. She underwent resurgery with ICG-assisted internal limiting membrane peeling and intraocular tamponade. Intraoperatively a large area of subretinal ICG was seen with subsequent RPE mottling and atrophy of the macula in the area involved during follow-up. This case demonstrates that subretinal migration of ICG is possible and can be toxic to RPE.
报告在黄斑手术治疗浆液性黄斑脱离过程中吲哚菁绿染料（ICG）的视网膜下迁移及随后的视网膜色素上皮（RPE）萎缩。一名65岁女性在接受视网膜前膜玻璃体视网膜手术后出现视网膜前膜残留和黄斑浆液性脱离。她接受了ICG辅助的内界膜剥除和眼内填充再手术。术中可见大面积ICG视网膜下迁移，随访期间受累区域出现黄斑RPE斑驳和萎缩。该病例表明ICG视网膜下迁移是可能的，并且对RPE具有毒性。
