Jin Ya-Sheng, Yin Shi-An
National Institute for Nutrition and Food Safety, Chinese Center for Disease Control and Prevention, Beijing 100050, China.
Wei Sheng Yan Jiu. 2005 Jul;34(4):422-4.
To study the effect of vitamin B6 status on selenium retention in tissues.
Weaning male Wistar, 4-week-old, fed with vitamin B6-selenium-deficient basal diet for 3 weeks was randomly divided into 6 groups. There were six experimental diets, that is basal diet (vitamin B6-selenium-deficient), basal diet supplemented with vitamin B6, and supplemented with Se 0.25 mg/kg as Na2 SeO4 and vitamin B6 0, 1.0 2.5 and 5.0 mg/kg diet as pyridoxine HCl for 4 weeks, three-days metabolic test was carried out before finished the study.
Compared with each group supplemented with vitamin B6, the vitamin B6 deficient groups had a significantly low body weight gain and diet availability, and lower selenium retention in heart, liver, and kidneys, however, the status of vitamin B6 had no significant effect on the weight and selenium retention in the testes. Vitamin B6 had no significant influence on the selenium apparent absorption and retention by the three days metabolic test.
Providing adequate vitamin B6 could be benefit for improving rat growth and development and increasing selenium retention in the tissues.
研究维生素B6状态对组织中硒保留的影响。
将4周龄断乳雄性Wistar大鼠用缺乏维生素B6和硒的基础饲料喂养3周后，随机分为6组。有六种实验饲料，即基础饲料（缺乏维生素B6和硒）、补充维生素B6的基础饲料，以及分别添加0、1.0、2.5和5.0mg/kg盐酸吡哆醇形式的维生素B6和0.25mg/kg亚硒酸钠形式的硒的饲料，喂养4周，在研究结束前进行为期三天的代谢试验。
与补充维生素B6的各组相比，缺乏维生素B6的组体重增加和饲料利用率显著降低，心脏、肝脏和肾脏中的硒保留量也较低，然而，维生素B6状态对睾丸重量和硒保留没有显著影响。通过为期三天的代谢试验，维生素B6对硒的表观吸收和保留没有显著影响。
提供充足的维生素B6有利于改善大鼠生长发育并增加组织中硒的保留。
