Wolffe A P, Tafuri S, Ranjan M, Familari M
Laboratory of Molecular Embryology, National Institute of Child Health and Human Development, NIH, Bethesda, MD 20892.
New Biol. 1992 Apr;4(4):290-8.
The Y-box factors interact specifically with both DNA and RNA. Biologically they have roles in both transcriptional and translational regulation. Conserved through evolution from prokaryotic to eukaryotic organisms they represent a new family of nucleic acid binding proteins.
Y盒因子能与DNA和RNA特异性结合。在生物学功能上,它们在转录调控和翻译调控中均发挥作用。从原核生物到真核生物,Y盒因子在进化过程中保持保守,代表了一类新的核酸结合蛋白家族。