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外伤性视神经病变的治疗——23例患者的研究

Management of traumatic optic neuropathy--a study of 23 patients.

作者信息

Mauriello J A, DeLuca J, Krieger A, Schulder M, Frohman L

机构信息

Department of Ophthalmology, University of Medicine and Dentistry of New Jersey, New Jersey Medical School, Newark 07107.

出版信息

Br J Ophthalmol. 1992 Jun;76(6):349-52. doi: 10.1136/bjo.76.6.349.

Abstract

Twenty three patients with traumatic optic neuropathy were managed by medical and surgical treatment as follows. High dose intravenous steroids were initiated in all patients. If visions did not improve significantly after 24 to 48 hours decompression of an optic nerve sheath haematoma by medial orbitotomy and neurosurgical decompression of the optic canal were considered based on computed tomographic scan findings. Nine of 16 patients who received steroids only showed significant improvement. One of three showed improvement on optic nerve decompression after steroid failure; three or four showed improvement on optic nerve decompression after steroid failure; three or four showed improvement with combined optic nerve sheath decompression by the medial orbitotomy and decompression of the optic canal by frontal craniotomy. A lucid interval of vision after injury and an enlarged optic nerve sheath were associated with an improved prognosis. Five of the 23 patients had a lucid interval and all five had a final improved vision, while only five of 18 patients without a lucid interval improved. Similarly seven of the nine with an enlarged optic nerve sheath showed improvement while only three of 10 patients (three bilateral cases) who presented with no light perception improved with medical and surgical treatment. While a prospective controlled study of the management of traumatic optic neuropathy is necessary this preliminary study suggests that treatment of traumatic optic nerve sheath haematoma by optic nerve sheath decompression should be considered in selected patients.

摘要

23例创伤性视神经病变患者接受了如下药物和手术治疗。所有患者均开始使用大剂量静脉类固醇。如果在24至48小时后视力没有明显改善,则根据计算机断层扫描结果考虑通过内侧眶切开术对视神经鞘血肿进行减压以及对视神经管进行神经外科减压。仅接受类固醇治疗的16例患者中有9例显示出明显改善。3例中1例在类固醇治疗失败后经视神经减压后有所改善;3或4例在类固醇治疗失败后经视神经减压后有所改善;3或4例通过内侧眶切开术联合视神经鞘减压和额部开颅术对视神经管减压后有所改善。受伤后视力清醒期和视神经鞘增大与预后改善相关。23例患者中有5例有视力清醒期,所有5例最终视力均得到改善,而18例无视力清醒期的患者中只有5例有所改善。同样,9例视神经鞘增大的患者中有7例显示出改善,而10例无光感患者(3例双侧病例)中只有3例经药物和手术治疗后有所改善。虽然有必要对视神经病变的治疗进行前瞻性对照研究,但这项初步研究表明,对于部分患者应考虑通过视神经鞘减压治疗创伤性视神经鞘血肿。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/afa2/504284/398c8c53a838/brjopthal00054-0029-a.jpg

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