Karateke Ates, Haliloglu Berna, Atay Vedat, Gurbuz Ayse, Kir Gozde
Department of Gynecologic Oncology, Zeynep Kamil Women's and Children Hospital, and Department of Obstetrics and Gynecology, GATA Haydarpasa Medical School, Uskudar, Istanbul, Turkey.
Gynecol Oncol. 2005 Dec;99(3):778-81. doi: 10.1016/j.ygyno.2005.08.009. Epub 2005 Oct 17.
Microglandular adenocarcinoma is a rare type of endometrium carcinoma and had some potential diagnostic problems with difficulties in discriminating from some malign and benign lesions of cervix.
A 70-year-old woman misdiagnosed as cervical adenocarcinoma was referred to our clinic, and the lesion was ultimately evaluated as microglandular adenocarcinoma in repeat of endometrial curettage specimen. Postoperatively, histopathologic examination of specimen revealed grade 1 microglandular adenocarcinoma. To our best knowledge, this is the twelfth case of uterine carcinoma simulating microglandular hyperplasia in the literature.
Because microglandular adenocarcinoma can be confused with benign lesions like microglandular hyperplasia and malignant lesions of cervix, we aim to discuss the clinical, demographic and immunohistochemical characteristics of the patients with microglandular adenocarcinoma useful in differential diagnosis.
微腺型腺癌是一种罕见的子宫内膜癌类型，在与宫颈的一些良恶性病变鉴别时存在一些潜在的诊断问题。
一名70岁被误诊为宫颈腺癌的女性被转诊至我院，在对子宫内膜刮宫标本复查时病变最终被评估为微腺型腺癌。术后，标本的组织病理学检查显示为1级微腺型腺癌。据我们所知，这是文献中第12例模拟微腺型增生的子宫癌病例。
由于微腺型腺癌可与微腺型增生等良性病变以及宫颈恶性病变相混淆，我们旨在讨论有助于鉴别诊断的微腺型腺癌患者的临床、人口统计学和免疫组化特征。
