Manning David W, Chiang P P, Martell J M, Galante J O, Harris W H
Section of Orthopaedic Surgery and Rehabilitative Medicine, The University of Chicago Medical Center, IL 60637, USA.
J Arthroplasty. 2005 Oct;20(7):880-6. doi: 10.1016/j.arth.2005.03.033.
In this study, we compare the in vivo wear performance of electron beam-irradiated, postirradiation-melted, highly cross-linked polyethylene (HXLPE) and traditional UHMWPE via the Martell method. Seventy hips with HXLPE performed at the Massachusetts General Hospital had 138 radiograph pairs for wear analysis and a 31.2-month average follow-up (range, 24-44 months). An age-matched, sex-matched, and body mass index-matched subgroup of 111 hips with 214 acceptable radiograph pairs and a 4-year follow-up from our previously published study on traditional polyethylene performed at Rush-Presbyterian-St. Luke's Medical Center served as a control group. Martell wear analysis was performed for each group. Overall and steady-state wear rates were compared via a specialized t test. The steady-state wear in the HXLPE arm was observed after 2.0 years, was 0.007 mm/y, and was significantly less than the steady-state wear in the traditional arm (0.174 mm/y) (P = .003). Highly cross-linked polyethylene penetration rate was not affected by sex, age, activity, or body mass index by Mann-Whitney analysis.
在本研究中，我们通过马特尔方法比较了电子束辐照、辐照后熔融的高交联聚乙烯（HXLPE）与传统超高分子量聚乙烯（UHMWPE）的体内磨损性能。在马萨诸塞州总医院接受HXLPE治疗的70例髋关节有138对X线片用于磨损分析，平均随访31.2个月（范围24 - 44个月）。来自我们之前在拉什长老会圣卢克医疗中心发表的关于传统聚乙烯的研究中，111例年龄匹配、性别匹配和体重指数匹配的髋关节亚组，有214对可接受的X线片并进行了4年随访，作为对照组。对每组进行马特尔磨损分析。通过专门的t检验比较总体磨损率和稳态磨损率。HXLPE组在2.0年后观察到稳态磨损，为0.007mm/年，显著低于传统组的稳态磨损（0.174mm/年）（P = .003）。通过曼 - 惠特尼分析，高交联聚乙烯的磨损率不受性别、年龄、活动或体重指数的影响。
