Kroczek Kacper, Turek Paweł, Mazur Damian, Szczygielski Jacek, Filip Damian, Brodowski Robert, Balawender Krzysztof, Przeszłowski Łukasz, Lewandowski Bogumił, Orkisz Stanisław, Mazur Artur, Budzik Grzegorz, Cebulski Józef, Oleksy Mariusz
Doctoral School of Engineering and Technical Sciences, Rzeszow University of Technology, 35-959 Rzeszow, Poland.
Faculty of Mechanical Engineering and Aeronautics, Rzeszow University of Technology, 35-959 Rzeszow, Poland.
Polymers (Basel). 2022 Apr 9;14(8):1526. doi: 10.3390/polym14081526.
Tissue engineering is an interdisciplinary field of science that has developed very intensively in recent years. The first part of this review describes materials with medical and dental applications from the following groups: metals, polymers, ceramics, and composites. Both positive and negative sides of their application are presented from the point of view of medical application and mechanical properties. A variety of techniques for the manufacture of biomedical components are presented in this review. The main focus of this work is on additive manufacturing and 3D printing, as these modern techniques have been evaluated to be the best methods for the manufacture of medical and dental devices. The second part presents devices for skull bone reconstruction. The materials from which they are made and the possibilities offered by 3D printing in this field are also described. The last part concerns dental transitional implants (scaffolds) for guided bone regeneration, focusing on polylactide-hydroxyapatite nanocomposite due to its unique properties. This section summarises the current knowledge of scaffolds, focusing on the material, mechanical and biological requirements, the effects of these devices on the human body, and their great potential for applications.
组织工程学是近年来发展十分迅速的一门跨学科科学领域。本综述的第一部分描述了以下几类具有医学和牙科应用的材料：金属、聚合物、陶瓷和复合材料。从医学应用和力学性能的角度介绍了它们应用的优缺点。本综述介绍了多种生物医学部件的制造技术。这项工作的主要重点是增材制造和3D打印，因为这些现代技术已被评估为制造医疗和牙科设备的最佳方法。第二部分介绍了颅骨重建装置。还描述了其制造材料以及3D打印在该领域提供的可能性。最后一部分涉及用于引导骨再生的牙科过渡植入物（支架），由于其独特性能，重点介绍了聚乳酸-羟基磷灰石纳米复合材料。本节总结了目前关于支架的知识，重点关注材料、力学和生物学要求、这些装置对人体的影响及其巨大的应用潜力。
